Concepedia

Binding Site Complementarity

Binding Site Complementarity is a biochemical principle defining the precise structural and chemical compatibility between an enzyme's active site and its substrate, enabling selective molecular recognition and catalytic specificity through spatial and energetic optimization of intermolecular interactions.

89

Publications

5.7K

Citations

382

Authors

149

Institutions

Publications per year

2017–2026

10

Variants

Active Site Complementarity

Parents

Publications

89

The binding site for C1q on IgG

Alexander Duncan, Greg Winter · Nature · 1988 · 562 citations

, , +8

Impact of MicroRNA Levels, Target-Site Complementarity, and Cooperativity on Competing Endogenous RNA-Regulated Gene Expression

Rémy Denzler, Sean E. McGeary, Alexandra C. Title et al. · Molecular Cell · 2016 · 342 citations · Full text

, , +17

Model Studies in Molecular Recognition

Julius Rebek · Science · 1987 · 254 citations

, , +17

On the nature of antibody combining sites: Unusual structural features that may confer on these sites an enhanced capacity for binding ligands

Eduardo A. Padlan · Proteins Structure Function and Bioinformatics · 1990 · 232 citations

, , +17

Engineered iron oxide-adhesion mutants of the Escherichia coli phage lambda receptor.

Stanley Brown · Proceedings of the National Academy of Sciences · 1992 · 226 citations

, , +16

1–5 of 89

Authors

382

  1. GV
    Gert Vriend

    Radboud University Nijmegen, Netherlands

    2 publications · 250 citations

    2

    h-index

  2. SC
    Sylvie Chevalier

    Université de Rouen Normandie, France

    2 publications · 80 citations

    2

    h-index

  3. VM
    V. M. Sobolev

    Weizmann Institute of Science, Israel

    2 publications · 250 citations

    2

    h-index

  4. CD
    Caroline Diveu

    Inserm, France

    2 publications · 80 citations

    2

    h-index

  5. RC
    Rebecca C. Wade

    Heidelberg Institute for Theoretical Studies, Germany

    2 publications · 250 citations

    2

    h-index

1–5 of 382

Institutions

149

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    10 publications

    1.6K citations

  2. University of California, San Francisco

    San Francisco, United States

    4 h-index

    17 publications

    1.2K citations

  3. University of Washington

    Seattle, United States

    3 h-index

    9 publications

    797 citations

  4. Humboldt-Universität zu Berlin

    Berlin, Germany

    2 h-index

    6 publications

    322 citations

  5. California Institute of Technology

    Pasadena, United States

    2 h-index

    8 publications

    236 citations

  6. GW Pharmaceuticals (United Kingdom)

    Cambridge, United Kingdom

    2 h-index

    8 publications

    148 citations

  7. Johns Hopkins University

    Baltimore, United States

    2 h-index

    6 publications

    132 citations

  8. University of California, Berkeley

    Berkeley, United States

    2 h-index

    2 publications

    108 citations

1–8 of 149

Venues

  1. Journal of Biological Chemistry

    JBC · 12 publications · 617 citations

    12

    h-index

  2. Proteins Structure Function and Bioinformatics

    5 publications · 631 citations

    5

    h-index

  3. Nucleic Acids Research

    4 publications · 172 citations

    4

    h-index

  4. The Journal of Immunology

    JI · 4 publications · 226 citations

    4

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 489 citations

    3

    h-index

1–5