Concepedia

Benchmarking Binding Affinity Models

Benchmarking Binding Affinity Models is a systematic evaluation framework that, as a subclass of computational model assessment methods, specifically quantifies and compares the predictive accuracy, generalizability, and robustness of binding affinity models using standardized datasets, tasks, and performance metrics within the domain of molecular interaction modeling.

29

Publications

2.6K

Citations

149

Authors

70

Institutions

Publications per year

2017–2026

17

Parents

Publications

29

Boltz-2: Towards Accurate and Efficient Binding Affinity Prediction

Saro Passaro, Gabriele Corso, Jeremy Wohlwend et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2025 · 447 citations · Full text

, , +15

MHCflurry: Open-Source Class I MHC Binding Affinity Prediction

Timothy J. O’Donnell, Alex Rubinsteyn, Maria Bonsack et al. · Cell Systems · 2018 · 429 citations · Full text

, , +12

GraphProt: modeling binding preferences of RNA-binding proteins

Daniel Maticzka, Sita J. Lange, Fabrizio Costa et al. · Genome biology · 2014 · 320 citations · Full text

, , +14

A Community Resource Benchmarking Predictions of Peptide Binding to MHC-I Molecules

Bjoern Peters, Huynh‐Hoa Bui, Sune Pletscher-Frankild et al. · PLoS Computational Biology · 2006 · 291 citations · Full text

, , +17

SFCscore<sup><i>RF</i></sup>: A Random Forest-Based Scoring Function for Improved Affinity Prediction of Protein–Ligand Complexes

David Zilian, Christoph Sotriffer · Journal of Chemical Information and Modeling · 2013 · 179 citations

, , +17

1–5 of 29

Authors

149

  1. MN
    Morten Nielsen

    Technical University of Denmark, Denmark

    4 publications · 561 citations

    4

    h-index

  2. BP
    Bjoern Peters

    La Jolla Institute for Immunology, United States

    4 publications · 561 citations

    4

    h-index

  3. AS
    Alessandro Sette

    La Jolla Institute for Immunology, United States

    3 publications · 461 citations

    3

    h-index

  4. OL
    Ole Lund

    Technical University of Denmark, Denmark

    3 publications · 461 citations

    3

    h-index

  5. JS
    John Sidney

    La Jolla Institute for Immunology, United States

    3 publications · 461 citations

    3

    h-index

1–5 of 149

Institutions

70

  1. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    6 publications

    117 citations

  2. Technical University of Denmark

    Kongens Lyngby, Denmark

    3 h-index

    14 publications

    2.6K citations

  3. German Center for Infection Research

    Braunschweig, Germany

    2 h-index

    4 publications

    910 citations

  4. National University of General San Martín

    Buenos Aires, Argentina

    2 h-index

    11 publications

    1.6K citations

  5. Heidelberg University

    Heidelberg, Germany

    2 h-index

    5 publications

    936 citations

  6. Janssen (Belgium)

    Beerse, Belgium

    2 h-index

    5 publications

    281 citations

  7. Medical University of South Carolina

    Charleston, United States

    2 h-index

    2 publications

    455 citations

  8. La Jolla Institute for Immunology

    San Diego, United States

    2 h-index

    11 publications

    2.6K citations

1–8 of 70

Venues

  1. Journal of Chemical Information and Modeling

    JCIM · 4 publications · 326 citations

    4

    h-index

  2. Bioinformatics

    3 publications · 268 citations

    3

    h-index

  3. Protein Science

    PS · 2 publications · 69 citations

    2

    h-index

  4. Briefings in Bioinformatics

    2 publications · 35 citations

    2

    h-index

  5. PLoS Computational Biology

    2 publications · 308 citations

    2

    h-index

1–5