Concepedia

Bayesian Fine-mapping

Bayesian Fine-Mapping is a statistical framework for genetic fine-mapping that uses Bayesian inference to compute posterior probabilities of causality for genetic variants, distinguishing itself from frequentist approaches by incorporating prior knowledge and quantifying uncertainty in a probabilistic manner.

28

Publications

1.8K

Citations

240

Authors

113

Institutions

Publications per year

2017–2026

19

Parents

Publications

28

Probabilistic fine-mapping of transcriptome-wide association studies

Nicholas Mancuso, Malika Freund, Ruth Johnson et al. · Nature Genetics · 2019 · 444 citations · Full text

, , +13

Fine Mapping Causal Variants with an Approximate Bayesian Method Using Marginal Test Statistics

Wenan Chen, Beth R. Larrabee, Inna G. Ovsyannikova et al. · Genetics · 2015 · 261 citations · Full text

, , +12

Functional annotation and Bayesian fine-mapping reveals candidate genes for important agronomic traits in Holstein bulls

Jicai Jiang, John B. Cole, Ellen Freebern et al. · Communications Biology · 2019 · 182 citations · Full text

, , +17

GWAS and fine-mapping of livability and six disease traits in Holstein cattle

Ellen Freebern, Daniel Jordan de Abreu Santos, Lingzhao Fang et al. · BMC Genomics · 2020 · 145 citations · Full text

, , +17

Bayesian Fine-Scale Mapping of Disease Loci, by Hidden Markov Models

Andrew P. Morris, John C. Whittaker, David J. Balding · The American Journal of Human Genetics · 2000 · 88 citations · Full text

, , +14

1–5 of 28

Authors

240

  1. CW
    Chris Wallace

    University of Cambridge, United Kingdom

    4 publications · 166 citations

    4

    h-index

  2. AP
    Andrew P. Morris

    Centre for Human Genetics, United Kingdom

    3 publications · 154 citations

    3

    h-index

  3. JC
    John C. Whittaker

    London School of Hygiene & Tropical Medicine, United Kingdom

    3 publications · 130 citations

    3

    h-index

  4. SS
    Stephen Sawcer

    University of Cambridge, United Kingdom

    2 publications · 86 citations

    2

    h-index

  5. DJ
    David J. Balding

    University College London, United Kingdom

    2 publications · 119 citations

    2

    h-index

1–5 of 240

Institutions

113

  1. University of Cambridge

    Cambridge, United Kingdom

    6 h-index

    33 publications

    1.5K citations

  2. MRC Biostatistics Unit

    Cambridge, United Kingdom

    5 h-index

    11 publications

    445 citations

  3. University of Oxford

    Oxford, United Kingdom

    3 h-index

    16 publications

    570 citations

  4. Centre for Human Genetics

    Oxford, United Kingdom

    3 h-index

    15 publications

    531 citations

  5. University of Manchester

    Manchester, United Kingdom

    3 h-index

    5 publications

    169 citations

  6. Beltsville Agricultural Research Center

    Beltsville, United States

    2 h-index

    6 publications

    944 citations

  7. Agricultural Research Service

    Washington, United States

    2 h-index

    6 publications

    944 citations

  8. Tulane University

    New Orleans, United States

    2 h-index

    9 publications

    177 citations

1–8 of 113

Venues

  1. Genetics

    4 publications · 375 citations

    4

    h-index

  2. Communications Biology

    2 publications · 209 citations

    2

    h-index

  3. Genetic Epidemiology

    2 publications · 53 citations

    2

    h-index

  4. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 2 publications · 67 citations

    2

    h-index

  5. The American Journal of Human Genetics

    AJHG · 2 publications · 127 citations

    2

    h-index

1–5