Concepedia

Bayesian Efficacy Monitoring

Bayesian Efficacy Monitoring is a statistical methodology within Bayesian adaptive trial design that sequentially evaluates accumulating evidence to assess the probability of treatment efficacy relative to predefined decision criteria, enabling dynamic, data-driven modifications to ongoing clinical trials.

27

Publications

2.2K

Citations

104

Authors

55

Institutions

Publications per year

2017–2026

8

Parents

Publications

27

Bayesian Approaches to Randomized Trials

David J. Spiegelhalter, Laurence S. Freedman, Mahesh Parmar · Journal of the Royal Statistical Society Series A (Statistics in Society) · 1994 · 728 citations

, , +16

Bayesian sequential monitoring designs for single‐arm clinical trials with multiple outcomes

Peter F. Thall, Richard Simon, Elihu H. Estey · Statistics in Medicine · 1995 · 301 citations

, , +14

Applying Bayesian ideas in drug development and clinical trials

David J. Spiegelhalter, Laurence S. Freedman, Mahesh Parmar · Statistics in Medicine · 1993 · 131 citations

, , +14

The chart trials: Bayesian design and monitoring in practice

Mahesh Parmar, David J. Spiegelhalter, Laurence S. Freedman · Statistics in Medicine · 1994 · 110 citations

, , +15

The what, why and how of bayesian clinical trials monitoring

Laurence S. Freedman, David J. Spiegelhalter, Mahesh Parmar · Statistics in Medicine · 1994 · 100 citations

, , +16

1–5 of 27

Authors

104

  1. DJ
    David J. Spiegelhalter

    MRC Biostatistics Unit, United Kingdom

    6 publications · 1.2K citations

    6

    h-index

  2. LS
    Laurence S. Freedman

    Sheba Medical Center, Israel

    5 publications · 1.1K citations

    5

    h-index

  3. MP
    Mahesh Parmar

    University College London, United Kingdom

    5 publications · 1.1K citations

    5

    h-index

  4. RS
    Richard Simon

    National Cancer Institute, United States

    3 publications · 473 citations

    3

    h-index

  5. PF
    Peter F. Thall

    The University of Texas MD Anderson Cancer Center, United States

    3 publications · 387 citations

    3

    h-index

1–5 of 104

Institutions

55

  1. National Cancer Institute

    Bethesda, United States

    7 h-index

    10 publications

    1.6K citations

  2. MRC Biostatistics Unit

    Cambridge, United Kingdom

    5 h-index

    5 publications

    438 citations

  3. The University of Texas MD Anderson Cancer Center

    Houston, United States

    4 h-index

    13 publications

    893 citations

  4. National Institutes of Health

    Bethesda, United States

    2 h-index

    2 publications

    401 citations

  5. United States Food and Drug Administration

    Silver Spring, United States

    2 h-index

    5 publications

    161 citations

  6. MRC Cancer Unit

    Cambridge, United Kingdom

    2 h-index

    2 publications

    241 citations

  7. Emory University

    Atlanta, United States

    2 h-index

    5 publications

    119 citations

  8. University of Minnesota

    Minneapolis, United States

    2 h-index

    3 publications

    91 citations

1–8 of 55

Venues

  1. Statistics in Medicine

    9 publications · 800 citations

    9

    h-index

  2. Pharmaceutical Statistics

    2 publications · 45 citations

    2

    h-index

  3. Statistics in Biopharmaceutical Research

    SBR · 1 publications · 17 citations

    1

    h-index

  4. Biometrics

    1 publications · 11 citations

    1

    h-index

  5. British Journal of Clinical Pharmacology

    BJCP · 1 publications · 22 citations

    1

    h-index

1–5