Concepedia

Bayesian Dose-finding

Bayesian Dose-Finding is a statistical methodology within clinical trial design that uses Bayesian inference to sequentially update the probability of dose-toxicity and dose-efficacy relationships, thereby identifying an optimal dose by synthesizing accumulating trial data with prior knowledge.

127

Publications

7.5K

Citations

359

Authors

195

Institutions

Publications per year

2017–2026

36

Variants

Bayesian Dose-finding Design

Parents

Publications

127

Dose‐Finding Based on Efficacy–Toxicity Trade‐Offs

Peter F. Thall, John D. Cook · Biometrics · 2004 · 510 citations

, , +13

Critical aspects of the Bayesian approach to phase I cancer trials

Beat Neuenschwander, Michael Branson, Thomas Gsponer · Statistics in Medicine · 2008 · 436 citations · Full text

, , +12

Bayesian optimal interval designs for phase I clinical trials

Suyu Liu, Ying Yuan · Journal of the Royal Statistical Society Series C (Applied Statistics) · 2014 · 344 citations

, , +14

A Strategy for Dose-Finding and Safety Monitoring Based on Efficacy and Adverse Outcomes in Phase I/II Clinical Trials

Peter F. Thall, Kathy Russell · Biometrics · 1998 · 278 citations

, , +17

A modified toxicity probability interval method for dose-finding trials

Yuan Ji, Ping Liu, Yisheng Li et al. · Clinical Trials · 2010 · 273 citations · Full text

, , +10

1–5 of 127

Authors

359

  1. YY
    Ying Yuan

    The University of Texas MD Anderson Cancer Center, United States

    23 publications · 1.8K citations

    18

    h-index

  2. PF
    Peter F. Thall

    The University of Texas MD Anderson Cancer Center, United States

    13 publications · 1.4K citations

    13

    h-index

  3. SZ
    Sarah Zohar

    Inserm, France

    11 publications · 391 citations

    10

    h-index

  4. YJ
    Yuan Ji

    Endeavor Health, United States

    9 publications · 821 citations

    9

    h-index

  5. GY
    Guosheng Yin

    University of Hong Kong, Hong Kong SAR China

    9 publications · 910 citations

    9

    h-index

1–5 of 359

Institutions

195

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    31 h-index

    134 publications

    10K citations

  2. Inserm

    Paris, France

    11 h-index

    33 publications

    944 citations

  3. Université Paris Cité

    Paris, France

    11 h-index

    36 publications

    937 citations

  4. Sorbonne Université

    Paris, France

    11 h-index

    21 publications

    714 citations

  5. Kyoto University

    Kyoto, Japan

    7 h-index

    7 publications

    238 citations

  6. Novartis (Switzerland)

    Basel, Switzerland

    7 h-index

    20 publications

    1.8K citations

  7. Centre de Recherche des Cordeliers

    Paris, France

    7 h-index

    13 publications

    459 citations

  8. Louisiana State University

    Baton Rouge, United States

    5 h-index

    5 publications

    179 citations

1–8 of 195

Venues

  1. Statistics in Medicine

    27 publications · 1.4K citations

    20

    h-index

  2. Biometrics

    15 publications · 1.9K citations

    15

    h-index

  3. Journal of Biopharmaceutical Statistics

    JBS · 11 publications · 440 citations

    11

    h-index

  4. 9

    h-index

  5. Pharmaceutical Statistics

    8 publications · 300 citations

    8

    h-index

1–5