Concepedia

Bacterial Clamp Loader

A Bacterial Clamp Loader is a specialized protein complex that functions as a molecular matchmaker in DNA replication by assembling the sliding clamp onto primed DNA templates, distinguished from other clamp loaders by its exclusive presence and mechanistic adaptation within bacterial replication systems.

34

Publications

3.2K

Citations

117

Authors

42

Institutions

Publications per year

2017–2026

5

Variants

Bacterial Gamma Complex

Parents

Publications

34

AAA<sup>+</sup>: A Class of Chaperone-Like ATPases Associated with the Assembly, Operation, and Disassembly of Protein Complexes

Andrew F. Neuwald, L. Aravind, John L. Spouge et al. · Genome Research · 1999 · 1.8K citations · Full text

, , +17

Did DNA replication evolve twice independently?

Detlef D. Leipe, L. Aravind, Eugene V. Koonin · Nucleic Acids Research · 1999 · 351 citations · Full text

, , +17

The DNA Replication Machine of a Gram-positive Organism

Irina Bruck, Mike O’Donnell · Journal of Biological Chemistry · 2000 · 98 citations · Full text

, , +17

Atomic Structure of the Clamp Loader Small Subunit from Pyrococcus furiosus

Takuji Oyama, Yoshizumi Ishino, Isaac Cann et al. · Molecular Cell · 2001 · 75 citations · Full text

, , +16

Structural analysis of the inactive state of the <i>Escherichia coli</i> DNA polymerase clamp-loader complex

Steven L. Kazmirski, Marjetka Podobnik, Tanya F. Weitze et al. · Proceedings of the National Academy of Sciences · 2004 · 73 citations · Full text

, , +17

1–5 of 34

Authors

117

  1. MO
    Mike O’Donnell

    Howard Hughes Medical Institute, United States

    9 publications · 451 citations

    9

    h-index

  2. LB
    Linda B. Bloom

    University of Florida, United States

    6 publications · 142 citations

    6

    h-index

  3. AF
    Andrew F. Neuwald

    University of Maryland, Baltimore, United States

    4 publications · 1.9K citations

    4

    h-index

  4. ST
    Susan T. Lovett

    Brandeis University, United States

    3 publications · 58 citations

    3

    h-index

  5. RM
    Robert McKenna

    University of Florida, United States

    3 publications · 74 citations

    3

    h-index

1–5 of 117

Institutions

42

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    9 h-index

    24 publications

    1.2K citations

  2. Rockefeller University

    New York, United States

    9 h-index

    24 publications

    1.1K citations

  3. University of Florida

    Gainesville, United States

    6 h-index

    26 publications

    714 citations

  4. National Institutes of Health

    Bethesda, United States

    3 h-index

    7 publications

    8.1K citations

  5. Cold Spring Harbor Laboratory

    Cold Spring Harbor, United States

    3 h-index

    6 publications

    7.4K citations

  6. National Center for Biotechnology Information

    Bethesda, United States

    3 h-index

    7 publications

    8.1K citations

  7. Lawrence Berkeley National Laboratory

    Berkeley, United States

    3 h-index

    8 publications

    536 citations

  8. Brandeis University

    Waltham, United States

    3 h-index

    17 publications

    333 citations

1–8 of 42

Venues

  1. Journal of Biological Chemistry

    JBC · 9 publications · 353 citations

    9

    h-index

  2. Nucleic Acids Research

    5 publications · 408 citations

    5

    h-index

  3. Molecular Microbiology

    3 publications · 77 citations

    3

    h-index

  4. Journal of Structural Biology

    2 publications · 41 citations

    2

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 124 citations

    2

    h-index

1–5