Concepedia

Backbone Solvation

Backbone Solvation is a biophysical process in structural biology that refers to the preferential interaction and stabilization of a macromolecular backbone, particularly in proteins or nucleic acids, by solvent molecules, predominantly water, through hydrogen bonding and electrostatic interactions that influence conformational stability and folding dynamics.

31

Publications

1.6K

Citations

116

Authors

52

Institutions

Publications per year

2017–2026

3

Parents

Publications

31

Physical reasons for the unusual α-helix stabilization afforded by charged or neutral polar residues in alanine-rich peptides

Jorge A. Vila, Daniel R. Ripoll, H. A. Scheraga · Proceedings of the National Academy of Sciences · 2000 · 151 citations · Full text

, , +17

Host‐guest scale of left‐handed polyproline II helix formation

Adam L. Rucker, Cara T. Pager, Margaret N. Campbell et al. · Proteins Structure Function and Bioinformatics · 2003 · 139 citations

, , +16

Role of backbone solvation and electrostatics in generating preferred peptide backbone conformations: Distributions of phi

Franc Avbelj, Robert L. Baldwin · Proceedings of the National Academy of Sciences · 2003 · 121 citations

, , +17

Role of Backbone Hydration and Salt-Bridge Formation in Stability of α-Helix in Solution

Tuhin Ghosh, Shekhar Garde, Angel E. Garcı́a · Biophysical Journal · 2003 · 107 citations · Full text

, , +14

Influence of Backbone Solvation on Small Angle Neutron Scattering from Polyelectrolyte Solutions

Brett D. Ermi, Eric J. Amis · Macromolecules · 1997 · 98 citations

, , +17

1–5 of 31

Authors

116

  1. RL
    Robert L. Baldwin

    Stanford University, United States

    3 publications · 201 citations

    3

    h-index

  2. FA
    Franc Avbelj

    National Institute of Chemistry, Slovenia

    3 publications · 247 citations

    3

    h-index

  3. SM
    Sean M. Decatur

    Mount Holyoke College, United States

    2 publications · 111 citations

    2

    h-index

  4. BM
    B. Montgomery Pettitt

    University of Houston, United States

    2 publications · 90 citations

    2

    h-index

  5. GB
    Gisele Baldissera

    Universidade Estadual Paulista (Unesp), Brazil

    1 publications · 13 citations

    1

    h-index

1–5 of 116

Institutions

52

  1. National Institute of Chemistry

    Ljubljana, Slovenia

    3 h-index

    5 publications

    426 citations

  2. Stanford Medicine

    Stanford, United States

    3 h-index

    5 publications

    380 citations

  3. Mount Holyoke College

    South Hadley, United States

    2 h-index

    7 publications

    412 citations

  4. University of Houston

    Houston, United States

    2 h-index

    6 publications

    330 citations

  5. Los Alamos National Laboratory

    Los Alamos, United States

    2 h-index

    4 publications

    280 citations

  6. California Institute of Technology

    Pasadena, United States

    2 h-index

    7 publications

    385 citations

  7. University of Southern California

    Los Angeles, United States

    1 h-index

    1 publications

    98 citations

  8. The University of Texas Medical Branch at Galveston

    Galveston, United States

    1 h-index

    1 publications

    75 citations

1–8 of 52

Venues

  1. Biochemistry

    4 publications · 215 citations

    4

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 330 citations

    3

    h-index

  3. Proteins Structure Function and Bioinformatics

    2 publications · 170 citations

    2

    h-index

  4. Physical Chemistry Chemical Physics

    PCCP · 2 publications · 88 citations

    2

    h-index

  5. Journal of Molecular Biology

    JMB · 2 publications · 134 citations

    2

    h-index

1–5