Concepedia

Autoantibody Diversification

Autoantibody Diversification is a biological process in which the immune system’s production of autoantibodies expands over time to target multiple distinct self-antigens through epitope spreading, thereby amplifying autoimmune reactivity beyond the initial antigenic trigger.

13

Publications

972

Citations

79

Authors

26

Institutions

Publications per year

2017–2026

2

Parents

Publications

13

Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus

Christopher M. Tipton, Christopher Fucile, Jaime Darce et al. · Nature Immunology · 2015 · 588 citations · Full text

, , +12

HLA class II phenotype controls diversification of the autoantibody response in primary Sjögren's syndrome (pSS)

Maureen Rischmueller, S. Lester, Zhen‐Jun Chen et al. · Clinical & Experimental Immunology · 1998 · 94 citations · Full text

, , +17

Evidence for multiple mechanisms of polyclonal T cell activation in murine lupus.

Ramandeep Singh, Beatrice H. Hahn, Betty P. Tsao et al. · Journal of Clinical Investigation · 1998 · 60 citations · Full text

, , +17

Nature of T cell epitopes in lupus antigens and HLA-DR determines autoantibody initiation and diversification

Zhenhuan Zhao, Ji-Ling Ren, Chao Dai et al. · Annals of the Rheumatic Diseases · 2018 · 45 citations · Full text

, , +17

Ro60 Peptides Induce Antibodies to Similar Epitopes Shared Among Lupus-Related Autoantigens

Umesh S. Deshmukh, Janet E. Lewis, Felicia Gaskin et al. · The Journal of Immunology · 2000 · 41 citations

, , +17

1–5 of 13

Authors

79

  1. CC
    Carol C. Kannapell

    University of Virginia, United States

    2 publications · 86 citations

    2

    h-index

  2. SM
    Shu Man Fu

    University of Virginia, United States

    2 publications · 86 citations

    2

    h-index

  3. FG
    Felicia Gaskin

    University of Virginia, United States

    2 publications · 86 citations

    2

    h-index

  4. TJ
    Thomas Jehle

    University Medical Center Freiburg, Germany

    1 publications · 13 citations

    1

    h-index

  5. PK
    Prashant K. Dhakephalkar

    Agharkar Research Institute, India

    1 publications · 41 citations

    1

    h-index

1–5 of 79

Institutions

26

  1. University of Virginia

    Charlottesville, United States

    2 h-index

    8 publications

    356 citations

  2. Emory University

    Atlanta, United States

    1 h-index

    9 publications

    5.3K citations

  3. Flinders Medical Centre

    Bedford Park, Australia

    1 h-index

    6 publications

    564 citations

  4. Weizmann Institute of Science

    Rehovot, Israel

    1 h-index

    4 publications

    40 citations

  5. Smith-Kettlewell Eye Research Institute

    San Francisco, United States

    1 h-index

    1 publications

    13 citations

  6. ARUP Laboratories (United States)

    Salt Lake City, United States

    1 h-index

    3 publications

    36 citations

  7. University of South Australia

    Adelaide, Australia

    1 h-index

    6 publications

    564 citations

  8. Johannes Gutenberg University Mainz

    Mainz, Germany

    1 h-index

    4 publications

    52 citations

1–8 of 26

Venues

  1. Scandinavian Journal of Immunology

    2 publications · 54 citations

    2

    h-index

  2. Clinica Chimica Acta

    CCA · 1 publications · 12 citations

    1

    h-index

  3. Clinical & Experimental Immunology

    CEI · 1 publications · 94 citations

    1

    h-index

  4. The Journal of Immunology

    JI · 1 publications · 41 citations

    1

    h-index

  5. Trends in Immunology

    1 publications · 22 citations

    1

    h-index

1–5