Concepedia

Assay Specificity Optimization

Assay Specificity Optimization is a methodological framework in diagnostic monoclonal antibody development that enhances the selective binding of antibodies to target antigens by minimizing cross-reactivity with non-target molecules through systematic refinement of assay conditions and reagent composition.

88

Publications

3.3K

Citations

517

Authors

154

Institutions

Publications per year

2017–2026

17

Parents

Publications

88

Stem‐Loop RT‐qPCR for miRNAs

Martha F. Kramer · Current Protocols in Molecular Biology · 2011 · 308 citations · Full text

, , +15

Development and application of a two-site enzyme immunoassay for the determination of 'total' activin-A concentrations in serum and follicular fluid

P. G. Knight, Shanthi Muttukrishna, Nigel P. Groome · Journal of Endocrinology · 1996 · 260 citations

, , +16

Deep, Quantitative Coverage of the Lysine Acetylome Using Novel Anti-acetyl-lysine Antibodies and an Optimized Proteomic Workflow

Tanya Svinkina, Hongbo Gu, Jeffrey C. Silva et al. · Molecular & Cellular Proteomics · 2015 · 188 citations · Full text

, , +17

Methods for reducing non-specific antibody binding in enzyme-linked immunosorbent assays

J. Gerry Kenna, Glenn N. Major, R.S. Williams · Journal of Immunological Methods · 1985 · 137 citations · Full text

, , +12

Antibody engineering by codon-based mutagenesis in a filamentous phage vector system

Scott Glaser, D E Yelton, William D. Huse · The Journal of Immunology · 1992 · 112 citations

, , +17

1–5 of 88

Authors

517

  1. CX
    Chuanlai Xu

    Jiangnan University, China

    3 publications · 70 citations

    3

    h-index

  2. HK
    Hua Kuang

    Jiangnan University, China

    3 publications · 70 citations

    3

    h-index

  3. BD
    Binodh DeSilva

    Bristol-Myers Squibb (United States), United States

    2 publications · 47 citations

    2

    h-index

  4. CM
    Charles Ming Lok Chan

    Prince of Wales Hospital, China

    2 publications · 39 citations

    2

    h-index

  5. RR
    Ronald R. Bowsher

    Eli Lilly (United States), United States

    2 publications · 38 citations

    2

    h-index

1–5 of 517

Institutions

154

  1. Amgen (United States)

    Thousand Oaks, United States

    5 h-index

    23 publications

    403 citations

  2. University of Massachusetts Chan Medical School

    Worcester, United States

    3 h-index

    7 publications

    288 citations

  3. Eli Lilly (United States)

    Indianapolis, United States

    3 h-index

    14 publications

    553 citations

  4. Jiangnan University

    Wuxi, China

    3 h-index

    15 publications

    350 citations

  5. Uppsala University

    Uppsala, Sweden

    2 h-index

    6 publications

    217 citations

  6. KTH Royal Institute of Technology

    Stockholm, Sweden

    2 h-index

    21 publications

    1.7K citations

  7. Queen Elizabeth Hospital

    Hong Kong, China

    2 h-index

    12 publications

    232 citations

  8. Broad Institute

    Cambridge, United States

    2 h-index

    9 publications

    1.5K citations

1–8 of 154

Venues

  1. Journal of Immunological Methods

    14 publications · 519 citations

    12

    h-index

  2. PubMed

    Repository · 7 publications · 167 citations

    7

    h-index

  3. Food and Agricultural Immunology

    5 publications · 100 citations

    5

    h-index

  4. 4

    h-index

  5. Bioanalysis

    BIO · 3 publications · 47 citations

    3

    h-index

1–5