Concepedia

Artificial Cofactor Design

Artificial Cofactor Design is a methodological framework within cofactor-dependent catalysis that involves the rational engineering of non-native cofactors to enhance or impart novel catalytic functions to enzymes, distinguishing it from natural cofactor utilization by its reliance on synthetic analogs with tailored chemical properties.

16

Publications

516

Citations

76

Authors

35

Institutions

Publications per year

2017–2026

10

Parents

Publications

16

Artificial Metalloenzyme Design with Unnatural Amino Acids and Non-Native Cofactors

Yang Yu, Cheng Hu, Lin Xia et al. · ACS Catalysis · 2018 · 105 citations

, , +17

Rationally engineered variants of S-adenosylmethionine (SAM) synthase: reduced product inhibition and synthesis of artificial cofactor homologues

Martin Dippe, Wolfgang Brandt, H. Rost et al. · Chemical Communications · 2015 · 51 citations

, , +17

Heterogeneous Systems Biocatalysis: The Path to the Fabrication of Self‐Sufficient Artificial Metabolic Cells

Fernando López‐Gallego, Erienne Jackson, Lorena Betancor · Chemistry - A European Journal · 2017 · 48 citations

, , +11

Enhanced Ene‐Reductase Activity through Alteration of Artificial Nicotinamide Cofactor Substituents

Sebastian A. Löw, Isabell Löw, Martin J. Weissenborn et al. · ChemCatChem · 2016 · 46 citations · Full text

, , +16

Cofactor‐Assisted Artificial Enzyme with Multiple Li‐Bond Networks for Sustainable Polysulfide Conversion in Lithium–Sulfur Batteries

Suya Zhou, Shuo Yang, Dong Cai et al. · Advanced Science · 2021 · 34 citations · Full text

, , +17

1–5 of 16

Authors

76

  1. HP
    Hannah Pollak

    Austrian Centre of Industrial Biotechnology (Austria), Austria

    1 publications · 29 citations

    1

    h-index

  2. LZ
    Lei Zhang

    Uppsala University, Sweden

    1 publications · 20 citations

    1

    h-index

  3. HL
    Horst Lechner

    University of Graz, Austria

    1 publications · 12 citations

    1

    h-index

  4. HN
    Huagui Nie

    Wenzhou University, China

    1 publications · 34 citations

    1

    h-index

  5. JW
    Jiangyun Wang

    Chinese Academy of Sciences, China

    1 publications · 105 citations

    1

    h-index

1–5 of 76

Institutions

35

  1. Institute of Biophysics

    Beijing, China

    1 h-index

    2 publications

    210 citations

  2. University of Groningen

    Groningen, The Netherlands

    1 h-index

    3 publications

    72 citations

  3. Institute of Process Engineering

    Beijing, China

    1 h-index

    1 publications

    23 citations

  4. Luleå University of Technology

    Luleå, Sweden

    1 h-index

    4 publications

    92 citations

  5. Iowa State University

    Ames, United States

    1 h-index

    3 publications

    42 citations

  6. Ikerbasque

    Bilbao, Spain

    1 h-index

    1 publications

    48 citations

  7. Austrian Centre of Industrial Biotechnology (Austria)

    Graz, Austria

    1 h-index

    4 publications

    116 citations

  8. Tianjin Institute of Industrial Biotechnology

    Tianjin, China

    1 h-index

    1 publications

    105 citations

1–8 of 35

Venues

  1. ACS Catalysis

    4 publications · 188 citations

    4

    h-index

  2. Chemical Communications

    ChemComm · 2 publications · 71 citations

    2

    h-index

  3. Journal of Molecular Catalysis B Enzymatic

    1 publications · 13 citations

    1

    h-index

  4. Chemistry Letters

    1 publications · 18 citations

    1

    h-index

  5. Advanced Science

    1 publications · 34 citations

    1

    h-index

1–5