Concepedia

Aptamer Discovery

Aptamer Discovery is a biologics discovery method that identifies single-stranded DNA or RNA molecules capable of binding to specific target molecules through high-affinity interactions, distinguished from other methods by its reliance on iterative in vitro selection processes such as SELEX.

668

Publications

38.1K

Citations

3.2K

Authors

1K

Institutions

Publications per year

2017–2026

307

Parents

Publications

668

A tenascin-C aptamer identified by tumor cell SELEX: Systematic evolution of ligands by exponential enrichment

Dion A. Daniels, Hang Chen, Brian J. Hicke et al. · Proceedings of the National Academy of Sciences · 2003 · 569 citations · Full text

, , +16

Selection of DNA Aptamers against Epithelial Cell Adhesion Molecule for Cancer Cell Imaging and Circulating Tumor Cell Capture

Yanling Song, Zhi Zhu, Yuan An et al. · Analytical Chemistry · 2013 · 507 citations

, , +17

Cell-Specific Aptamer Probes for Membrane Protein Elucidation in Cancer Cells

Dihua Shangguan, Zehui Cao, Ling Meng et al. · Journal of Proteome Research · 2008 · 462 citations · Full text

, , +16

Discovery of Aptamers Targeting the Receptor-Binding Domain of the SARS-CoV-2 Spike Glycoprotein

Yanling Song, Jia Song, Xinyu Wei et al. · Analytical Chemistry · 2020 · 456 citations · Full text

, , +17

Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2

Pierre Colas, Barak A. Cohen, Timm Jessen et al. · Nature · 1996 · 451 citations

, , +13

1–5 of 668

Authors

3.2K

  1. WT
    Weihong Tan

    Hunan University, China

    20 publications · 2.1K citations

    19

    h-index

  2. CY
    Chaoyong Yang

    Xiamen University, China

    16 publications · 1.7K citations

    15

    h-index

  3. HT
    H. Tom Soh

    University of California, Santa Barbara, United States

    14 publications · 1.7K citations

    14

    h-index

  4. YS
    Yanling Song

    Xiamen University, China

    13 publications · 1.5K citations

    13

    h-index

  5. AD
    Andrew D. Ellington

    The University of Texas at Austin, United States

    12 publications · 1.1K citations

    12

    h-index

1–5 of 3.2K

Institutions

1K

  1. Chinese Academy of Sciences

    Beijing, China

    20 h-index

    93 publications

    7K citations

  2. Hunan University

    Changsha, China

    20 h-index

    130 publications

    6.9K citations

  3. Xiamen University

    Xiamen, China

    16 h-index

    108 publications

    12.5K citations

  4. Central South University

    Changsha, China

    14 h-index

    72 publications

    3.5K citations

  5. The University of Texas at Austin

    Austin, United States

    14 h-index

    42 publications

    3.6K citations

  6. University of California, Santa Barbara

    Santa Barbara, United States

    13 h-index

    63 publications

    5.9K citations

  7. Shanghai Jiao Tong University

    Shanghai, China

    13 h-index

    45 publications

    3K citations

  8. University of Florida

    Gainesville, United States

    12 h-index

    67 publications

    10.6K citations

1–8 of 1K

Venues

  1. PLoS ONE

    33 publications · 2.1K citations

    27

    h-index

  2. Nucleic Acids Research

    28 publications · 2.5K citations

    27

    h-index

  3. Analytical Chemistry

    32 publications · 3.4K citations

    25

    h-index

  4. Molecular Therapy — Nucleic Acids

    27 publications · 1.4K citations

    22

    h-index

  5. Scientific Reports

    27 publications · 1.1K citations

    21

    h-index

1–5