Concepedia

Apoptotic Threshold Modulation

Apoptotic Threshold Modulation is a regulatory mechanism in cell biology that adjusts the sensitivity of a cell to apoptotic stimuli by altering the levels or activities of key signaling molecules that govern the commitment to programmed cell death.

40

Publications

2.4K

Citations

203

Authors

96

Institutions

Publications per year

2017–2026

4

Parents

Publications

40

Bcl-xS Antagonizes the Protective Effects of Bcl-xL

Andy J. Minn, Lawrence Boise, Craig B. Thompson · Journal of Biological Chemistry · 1996 · 200 citations · Full text

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Apoptotic threshold is lowered by p53 transactivation of caspase-6

Timothy K. MacLachlan, Wafik S. El‐Deiry · Proceedings of the National Academy of Sciences · 2002 · 163 citations

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Insights from Bcl-2 and Myc: malignancy involves abrogation of apoptosis as well as sustained proliferation.

Suzanne Cory, David L. Vaux, Andreas Strasser et al. · PubMed · 1999 · 150 citations

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Quinazoline-derived alpha1-adrenoceptor antagonists induce prostate cancer cell apoptosis via an alpha1-adrenoceptor-independent action.

Cynthia M. Benning, Natasha Kyprianou · PubMed · 2002 · 129 citations

, , +17

Bcl-2 is overexpressed and alters the threshold for apoptosis in a cholangiocarcinoma cell line

Denise M. Harnois, Florencia G. Que, Anna Celli et al. · Hepatology · 1997 · 129 citations · Full text

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1–5 of 40

Authors

203

  1. LB
    Lawrence Boise

    Emory University, United States

    2 publications · 236 citations

    2

    h-index

  2. TA
    Tristan A. Rodríguez

    Imperial College London, United Kingdom

    2 publications · 82 citations

    2

    h-index

  3. CM
    Clelia M. Riera

    Universidad Nacional de Córdoba, Argentina

    2 publications · 95 citations

    2

    h-index

  4. CM
    Cecília M. P. Rodrigues

    University of Lisbon, Portugal

    2 publications · 167 citations

    2

    h-index

  5. BP
    Bárbara Pernaute

    Imperial College London, United Kingdom

    2 publications · 82 citations

    2

    h-index

1–5 of 203

Institutions

96

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    5 publications

    642 citations

  2. University of Massachusetts Chan Medical School

    Worcester, United States

    2 h-index

    2 publications

    104 citations

  3. Imperial College London

    London, United Kingdom

    2 h-index

    11 publications

    361 citations

  4. Inserm

    Paris, France

    2 h-index

    14 publications

    345 citations

  5. Universidad Nacional de Córdoba

    Córdoba, Argentina

    2 h-index

    6 publications

    285 citations

  6. University of Manchester

    Manchester, United Kingdom

    2 h-index

    6 publications

    131 citations

  7. University of Chicago

    Chicago, United States

    2 h-index

    4 publications

    374 citations

  8. Mayo Clinic

    Rochester, United States

    2 h-index

    5 publications

    645 citations

1–8 of 96

Venues

  1. Journal of Biological Chemistry

    JBC · 4 publications · 420 citations

    4

    h-index

  2. PubMed

    Repository · 3 publications · 340 citations

    3

    h-index

  3. British Journal of Cancer

    BJC · 2 publications · 106 citations

    2

    h-index

  4. Cell Cycle

    2 publications · 43 citations

    2

    h-index

  5. Neoplasia

    1 publications · 24 citations

    2

    h-index

1–5