Concepedia

Apobec Enzymes

APOBEC Enzymes are a class of cytidine deaminase enzymes that catalyze the post-transcriptional deamination of cytosine to uracil in RNA substrates, thereby mediating RNA editing events critical to the regulation of gene expression.

443

Publications

39.8K

Citations

2.3K

Authors

671

Institutions

Publications per year

2017–2026

140

Variants

Apobec Family Cytidine Deaminases

Parents

Publications

443

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

Steven A. Roberts, Michael S. Lawrence, Leszek J. Klimczak et al. · Nature Genetics · 2013 · 1.2K citations · Full text

, , +8

Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells

Masamichi Muramatsu, V.S. Sankaranand, Shrikant Anant et al. · Journal of Biological Chemistry · 1999 · 1.2K citations · Full text

, , +15

Mutational signatures associated with tobacco smoking in human cancer

Ludmil B. Alexandrov, Young Seok Ju, Kerstin Haase et al. · Science · 2016 · 1.1K citations · Full text

, , +17

APOBEC3B is an enzymatic source of mutation in breast cancer

Michael B. Burns, Lela Lackey, Michael A. Carpenter et al. · Nature · 2013 · 876 citations

, , +8

RNA Editing Enzyme APOBEC1 and Some of Its Homologs Can Act as DNA Mutators

Reuben S. Harris, Svend K. Petersen‐Mahrt, Michael S. Neuberger · Molecular Cell · 2002 · 613 citations · Full text

, , +10

1–5 of 443

Authors

2.3K

  1. RS
    Reuben S. Harris

    University of Minnesota, United States

    51 publications · 6.4K citations

    35

    h-index

  2. NO
    Nicholas O. Davidson

    Washington University in St. Louis, United States

    24 publications · 3K citations

    21

    h-index

  3. LC
    Linda Chelico

    University of Saskatchewan, Canada

    25 publications · 1.5K citations

    20

    h-index

  4. HC
    Harold C. Smith

    University of Rochester, United States

    20 publications · 763 citations

    17

    h-index

  5. WL
    William L. Brown

    University of Minnesota, United States

    18 publications · 2.1K citations

    16

    h-index

1–5 of 2.3K

Institutions

671

  1. University of Minnesota

    Minneapolis, United States

    37 h-index

    292 publications

    40.7K citations

  2. National Institutes of Health

    Bethesda, United States

    26 h-index

    98 publications

    12.6K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    22 h-index

    59 publications

    5.8K citations

  4. University of California, San Francisco

    San Francisco, United States

    18 h-index

    62 publications

    7.1K citations

  5. University of Rochester

    Rochester, United States

    18 h-index

    74 publications

    3K citations

  6. University of Saskatchewan

    Saskatoon, Canada

    18 h-index

    73 publications

    3.5K citations

  7. National Cancer Institute

    Bethesda, United States

    16 h-index

    74 publications

    6.2K citations

  8. Kyoto University

    Kyoto, Japan

    14 h-index

    107 publications

    7K citations

1–8 of 671

Venues

  1. Journal of Biological Chemistry

    JBC · 57 publications · 6.4K citations

    43

    h-index

  2. Journal of Virology

    JVI · 34 publications · 3.6K citations

    29

    h-index

  3. Nucleic Acids Research

    24 publications · 1.6K citations

    21

    h-index

  4. Nature Communications

    17 publications · 1.8K citations

    16

    h-index

  5. Journal of Molecular Biology

    JMB · 17 publications · 994 citations

    16

    h-index

1–5