Concepedia

Antigen-binding Site Structure

Antigen-Binding Site Structure is a structural biological construct that specifies the three-dimensional configuration of variable regions within an antibody's paratope, distinguished by its precise molecular complementarity to a specific antigenic epitope, enabling selective molecular recognition and binding.

633

Publications

45.3K

Citations

2.8K

Authors

736

Institutions

Publications per year

2017–2026

59

Variants

Paratope Structure

Parents

Publications

633

Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation

Don C. Wiley, Ian A. Wilson, J.J. Skehel · Nature · 1981 · 1.6K citations

, , +16

The structure of an antigenic determinant in a protein

Ian A. Wilson, Henry Niman, Richard A. Houghten et al. · Cell · 1984 · 842 citations

, , +11

Emerging Principles for the Recognition of Peptide Antigens by MHC Class I Molecules

Masazumi Matsumura, Daved H. Fremont, Per A. Peterson et al. · Science · 1992 · 732 citations

, , +17

Antibody Multispecificity Mediated by Conformational Diversity

Leo C. James, Pietro Roversi, Dan S. Tawfik · Science · 2003 · 711 citations

, , +17

Three-dimensional structure of an antibody-antigen complex.

S. Sheriff, Enid W. Silverton, Eduardo A. Padlan et al. · Proceedings of the National Academy of Sciences · 1987 · 609 citations · Full text

, , +16

1–5 of 633

Authors

2.8K

  1. IA
    Ian A. Wilson

    Scripps Research Institute, United States

    26 publications · 5.4K citations

    23

    h-index

  2. RJ
    Roberto J. Poljak

    Institut Pasteur, France

    9 publications · 1.1K citations

    9

    h-index

  3. RA
    Roy A. Mariuzza

    Biotechnology Institute, United States

    9 publications · 978 citations

    9

    h-index

  4. MZ
    M. Zouhair Atassi

    Baylor College of Medicine, United States

    8 publications · 511 citations

    8

    h-index

  5. EA
    Elvin A. Kabat

    Columbia University, United States

    8 publications · 704 citations

    8

    h-index

1–5 of 2.8K

Institutions

736

  1. Scripps Research Institute

    San Diego, United States

    32 h-index

    207 publications

    28.9K citations

  2. National Institutes of Health

    Bethesda, United States

    25 h-index

    111 publications

    13.7K citations

  3. Harvard University

    Cambridge, United States

    23 h-index

    92 publications

    13.6K citations

  4. University of Oxford

    Oxford, United Kingdom

    20 h-index

    79 publications

    4.6K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    17 h-index

    92 publications

    5.6K citations

  6. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    15 h-index

    59 publications

    5.6K citations

  7. Institut Pasteur

    Paris, France

    15 h-index

    77 publications

    6.7K citations

  8. Weizmann Institute of Science

    Rehovot, Israel

    11 h-index

    35 publications

    2.3K citations

1–8 of 736

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 48 publications · 6.1K citations

    37

    h-index

  2. Journal of Biological Chemistry

    JBC · 54 publications · 3.5K citations

    35

    h-index

  3. Journal of Molecular Biology

    JMB · 39 publications · 3.4K citations

    28

    h-index

  4. The Journal of Immunology

    JI · 39 publications · 2K citations

    27

    h-index

  5. Journal of Virology

    JVI · 31 publications · 2.3K citations

    26

    h-index

1–5