Concepedia

Antigen Formulation Optimization

Antigen Formulation Optimization is the systematic refinement of antigen composition, delivery vehicles, adjuvants, and stabilizing agents within a vaccine candidate to maximize immunogenicity, stability, and safety while minimizing dose and reactogenicity.

20

Publications

892

Citations

145

Authors

37

Institutions

Publications per year

2017–2026

9

Parents

Publications

20

A computationally optimized broadly reactive antigen (COBRA) based H5N1 VLP vaccine elicits broadly reactive antibodies in mice and ferrets

Brendan M. Giles, Ted M. Ross · Vaccine · 2011 · 205 citations

, , +16

Phase 2 clinical trial of three formulations of tetravalent live-attenuated dengue vaccine in flavivirus-naïve adults

Wellington Sun, Dennis Cunningham, Steven S. Wasserman et al. · Human Vaccines · 2009 · 118 citations

, , +16

Montanide® ISA 720 vaccines: quality control of emulsions, stability of formulated antigens, and comparative immunogenicity of vaccine formulations

Aaron P. Miles, Holly McClellan, Kelly M. Rausch et al. · Vaccine · 2004 · 99 citations

, , +17

Single dose, polymeric, microparticle-based vaccines: the influence of formulation conditions on the magnitude and duration of the immune response to a protein antigen

A.G.A. Coombes · Vaccine · 1996 · 83 citations

, , +17

Hepatitis B Antigen Loaded Biodegradable Polymeric Nanoparticles: Formulation Optimization and In-vivo Immunization in BALB/c Mice

Hitesh Kumar Dewangan, Sanjay Singh, Lakshmi Maurya et al. · Current Drug Delivery · 2018 · 44 citations

, , +17

1–5 of 20

Authors

145

  1. TM
    Ted M. Ross

    University of Georgia, United States

    2 publications · 238 citations

    2

    h-index

  2. DC
    Dexiang Chen

    Program for Appropriate Technology in Health, United States

    2 publications · 60 citations

    2

    h-index

  3. DB
    David B. Volkin

    University of Kansas, United States

    2 publications · 45 citations

    2

    h-index

  4. SB
    Sangeeta B. Joshi

    University of Kansas, United States

    2 publications · 45 citations

    2

    h-index

  5. WT
    Wenjie Tan

    National Institute for Viral Disease Control and Prevention, China

    1 publications · 10 citations

    1

    h-index

1–5 of 145

Institutions

37

  1. University of Washington

    Seattle, United States

    2 h-index

    5 publications

    135 citations

  2. University of Kansas

    Lawrence, United States

    2 h-index

    12 publications

    267 citations

  3. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    2 h-index

    15 publications

    1.3K citations

  4. National Institute for Viral Disease Control and Prevention

    Beijing, China

    1 h-index

    7 publications

    70 citations

  5. University of Pittsburgh

    Pittsburgh, United States

    1 h-index

    2 publications

    410 citations

  6. SUNY Upstate Medical University

    Syracuse, United States

    1 h-index

    2 publications

    26 citations

  7. University of Virginia Health System

    Charlottesville, United States

    1 h-index

    9 publications

    189 citations

  8. Syracuse University

    Syracuse, United States

    1 h-index

    2 publications

    26 citations

1–8 of 37

Venues

  1. Vaccine

    4 publications · 411 citations

    4

    h-index

  2. Human Vaccines & Immunotherapeutics

    HV&I · 2 publications · 29 citations

    2

    h-index

  3. Human Vaccines

    2 publications · 154 citations

    2

    h-index

  4. PubMed

    Repository · 1 publications · 31 citations

    1

    h-index

  5. Journal of Pharmaceutical Sciences

    1 publications · 21 citations

    1

    h-index

1–5