Concepedia

Antibody-dependent Complement Deposition

Antibody-Dependent Complement Deposition is a molecular mechanism in adaptive immunity whereby the binding of antibodies to antigens on a pathogen surface directly initiates the assembly of complement components through recruitment of the C1 complex, distinguishing it from complement activation pathways independent of antibody specificity.

103

Publications

5.2K

Citations

1.1K

Authors

269

Institutions

Publications per year

2017–2026

28

Variants

Adcd

Parents

Publications

103

Thrombus formation induced by antibodies to β2-glycoprotein I is complement dependent and requires a priming factor

Fabio Fischetti, Paolo Durigutto, Valentina Pellis et al. · Blood · 2005 · 353 citations · Full text

, , +16

Human Antibodies Fix Complement to Inhibit Plasmodium falciparum Invasion of Erythrocytes and Are Associated with Protection against Malaria

Michelle J. Boyle, Linda Reiling, Gaoqian Feng et al. · Immunity · 2015 · 317 citations · Full text

, , +17

A high-throughput, bead-based, antigen-specific assay to assess the ability of antibodies to induce complement activation

Stephanie Fischinger, Jonathan K. Fallon, Ashlin R. Michell et al. · Journal of Immunological Methods · 2019 · 224 citations · Full text

, , +15

Insights into IgM-mediated complement activation based on in situ structures of IgM-C1-C4b

Thomas H. Sharp, Aimee L. Boyle, Christoph A. Diebolder et al. · Proceedings of the National Academy of Sciences · 2019 · 202 citations · Full text

, , +17

Small intestinal enteropathy with epithelial IgG and complement deposition in children with regressive autism

Franco Torrente, Paul Ashwood, Richard M. Day et al. · Molecular Psychiatry · 2002 · 201 citations

, , +17

1–5 of 103

Authors

1.1K

  1. GA
    Galit Alter

    Ragon Institute of MGH, MIT and Harvard, United States

    7 publications · 621 citations

    7

    h-index

  2. MD
    Michelle Darrieux

    Instituto Butantan, Brazil

    3 publications · 237 citations

    3

    h-index

  3. AG
    Andrew Gorringe

    Public Health England, United Kingdom

    3 publications · 84 citations

    3

    h-index

  4. HS
    Hendrik Streeck

    Ragon Institute of MGH, MIT and Harvard, United States

    3 publications · 396 citations

    3

    h-index

  5. TR
    Thomas R. Kozel

    University of Nevada, Reno, United States

    3 publications · 130 citations

    3

    h-index

1–5 of 1.1K

Institutions

269

  1. Ragon Institute of MGH, MIT and Harvard

    Cambridge, United States

    8 h-index

    37 publications

    3.7K citations

  2. National Institutes of Health

    Bethesda, United States

    6 h-index

    28 publications

    1.4K citations

  3. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    5 h-index

    19 publications

    815 citations

  4. Walter Reed Army Institute of Research

    Silver Spring, United States

    4 h-index

    17 publications

    499 citations

  5. The University of Queensland

    Brisbane, Australia

    3 h-index

    3 publications

    433 citations

  6. Monash University

    Melbourne, Australia

    3 h-index

    8 publications

    402 citations

  7. Imperial College London

    London, United Kingdom

    3 h-index

    6 publications

    259 citations

  8. Sanofi (United States)

    Bridgewater, United States

    3 h-index

    3 publications

    124 citations

1–8 of 269

Venues

  1. Infection and Immunity

    IAI · 12 publications · 642 citations

    12

    h-index

  2. Frontiers in Immunology

    7 publications · 158 citations

    7

    h-index

  3. PubMed

    Repository · 7 publications · 138 citations

    7

    h-index

  4. The Journal of Immunology

    JI · 6 publications · 153 citations

    6

    h-index

  5. Vaccine

    3 publications · 128 citations

    3

    h-index

1–5