Concepedia

Animal Model Engineering

Animal Model Engineering is a methodological framework within genetic research that enables the precise modification of genomic sequences in model organisms through the targeted application of engineered nucleases, such as Zinc Finger Nucleases, to establish specific phenotypic or disease-relevant genetic alterations.

114

Publications

6.9K

Citations

755

Authors

260

Institutions

Publications per year

2017–2026

29

Parents

Publications

114

Experimental strategies for the genetic dissection of complex traits in animal models

Ariel Darvasi · Nature Genetics · 1998 · 545 citations

, , +16

Role and interaction of connective tissue growth factor with transforming growth factor-? in persistent fibrosis: A mouse fibrosis model

Toshifumi Mori, Shigeru Kawara, Mikio Shinozaki et al. · Journal of Cellular Physiology · 1999 · 465 citations

, , +16

Genetic Groups in an Animal Model

R.A. Westell, R.L. Quaas, L.D. Van Vleck · Journal of Dairy Science · 1988 · 321 citations · Full text

, , +7

Mice transgenic for human angiotensin-converting enzyme 2 provide a model for SARS coronavirus infection.

Xiu Hong Yang, Wei Deng, Zan Tong et al. · PubMed · 2007 · 272 citations

, , +16

Genetically engineered large animal model for studying cone photoreceptor survival and degeneration in retinitis pigmentosa

Robert M. Petters, Curtis A. Alexander, Kevin D. Wells et al. · Nature Biotechnology · 1997 · 265 citations

, , +15

1–5 of 114

Authors

755

  1. EM
    Eric M. Walters

    University of Missouri, United States

    4 publications · 474 citations

    4

    h-index

  2. RS
    Randall S. Prather

    University of Missouri, United States

    3 publications · 420 citations

    3

    h-index

  3. KD
    Kevin D. Wells

    University of Missouri, United States

    3 publications · 553 citations

    3

    h-index

  4. LB
    Lawrence B. Schook

    University of Illinois Urbana-Champaign, United States

    2 publications · 225 citations

    2

    h-index

  5. JN
    Johan Neyts

    Rega Institute for Medical Research, Belgium

    2 publications · 48 citations

    2

    h-index

1–5 of 755

Institutions

260

  1. Harvard University

    Cambridge, United States

    5 h-index

    24 publications

    1.2K citations

  2. University of Missouri

    Columbia, United States

    5 h-index

    17 publications

    1.9K citations

  3. National Institutes of Health

    Bethesda, United States

    4 h-index

    10 publications

    541 citations

  4. University of Pennsylvania

    Philadelphia, United States

    4 h-index

    19 publications

    2.2K citations

  5. University of Michigan

    Ann Arbor, United States

    3 h-index

    8 publications

    245 citations

  6. University of Pittsburgh

    Pittsburgh, United States

    3 h-index

    17 publications

    469 citations

  7. Medizinische Hochschule Hannover

    Hanover, Germany

    3 h-index

    22 publications

    772 citations

  8. KU Leuven

    Leuven, Belgium

    3 h-index

    5 publications

    96 citations

1–8 of 260

Venues

  1. PubMed

    Repository · 8 publications · 525 citations

    8

    h-index

  2. PLoS ONE

    5 publications · 278 citations

    5

    h-index

  3. Journal of Visualized Experiments

    3 publications · 63 citations

    3

    h-index

  4. Journal of Virology

    JVI · 3 publications · 120 citations

    3

    h-index

  5. Scientific Reports

    2 publications · 114 citations

    2

    h-index

1–5