Concepedia

Amplification Cascades

Amplification Cascades is a biochemical signaling mechanism in which a sequential activation of intermediates leads to progressive signal enhancement, distinguishing it from simple amplification by enabling multiplicative gain through layered enzymatic steps.

42

Publications

2.1K

Citations

170

Authors

54

Institutions

Publications per year

2017–2026

20

Variants

Signal Amplification Cascades

Parents

Publications

42

A Nonenzymatic Hairpin DNA Cascade Reaction Provides High Signal Gain of mRNA Imaging inside Live Cells

Cuichen Wu, Sena Cansız, Liqin Zhang et al. · Journal of the American Chemical Society · 2015 · 330 citations · Full text

, , +15

Stacking nonenzymatic circuits for high signal gain

Xi Chen, Neima Briggs, Jeremy R. McLain et al. · Proceedings of the National Academy of Sciences · 2013 · 252 citations · Full text

, , +14

mTOR Generates an Auto-Amplification Loop by Triggering the βTrCP- and CK1α-Dependent Degradation of DEPTOR

Shanshan Duan, Jeffrey R. Skaar, Shafi Kuchay et al. · Molecular Cell · 2011 · 193 citations · Full text

, , +13

Ultrasensitive Detection of Transcription Factors Using Transcription-Mediated Isothermally Exponential Amplification-Induced Chemiluminescence

Fei Ma, Yong Yang, Chun‐yang Zhang · Analytical Chemistry · 2014 · 110 citations

, , +15

Ratiometric Electrochemiluminescent/Electrochemical Strategy for Sensitive Detection of MicroRNA Based on Duplex-Specific Nuclease and Multilayer Circuit of Catalytic Hairpin Assembly

Liping Zhu, Mengqian Zhang, Jing Ye et al. · Analytical Chemistry · 2020 · 91 citations

, , +17

1–5 of 42

Authors

170

  1. RY
    Ruo Yuan

    Southwest University, China

    2 publications · 30 citations

    4

    h-index

  2. YX
    Yun Xiang

    Southwest University, China

    2 publications · 30 citations

    4

    h-index

  3. WJ
    Wei Jiang

    Shandong University, China

    2 publications · 66 citations

    2

    h-index

  4. XX
    Xiaowen Xu

    Shandong University, China

    2 publications · 66 citations

    2

    h-index

  5. LW
    Lei Wang

    Shandong University, China

    2 publications · 57 citations

    2

    h-index

1–5 of 170

Institutions

54

  1. Southwest University

    Chongqing, China

    5 h-index

    15 publications

    449 citations

  2. Chinese Academy of Sciences

    Beijing, China

    4 h-index

    14 publications

    755 citations

  3. Shandong University

    Jinan, China

    3 h-index

    13 publications

    467 citations

  4. Hunan University

    Changsha, China

    3 h-index

    14 publications

    2.2K citations

  5. Deutsches Elektronen-Synchrotron DESY

    Hamburg, Germany

    2 h-index

    5 publications

    147 citations

  6. State Key Laboratory of Chemobiosensing and Chemometrics

    Changsha, China

    2 h-index

    9 publications

    531 citations

  7. Wuhan University

    Wuhan, China

    2 h-index

    8 publications

    212 citations

  8. Ministry of Education

    Sejong, South Korea

    1 h-index

    4 publications

    96 citations

1–8 of 54

Venues

  1. Analytical Chemistry

    6 publications · 351 citations

    6

    h-index

  2. Chemical Communications

    ChemComm · 4 publications · 157 citations

    4

    h-index

  3. Biosensors and Bioelectronics

    2 publications · 22 citations

    3

    h-index

  4. Sensors and Actuators B Chemical

    3 publications · 98 citations

    3

    h-index

  5. Chemical Engineering Journal

    2 publications · 75 citations

    2

    h-index

1–5