Concepedia

Amphiphysin Function

Amphiphysin Function is a molecular scaffolding mechanism that selectively mediates membrane curvature and dynamin recruitment during synaptic vesicle endocytosis, thereby facilitating membrane scission through spatial and temporal coordination of the endocytic machinery.

74

Publications

7.3K

Citations

386

Authors

151

Institutions

Publications per year

2017–2026

5

Parents

Publications

74

Functional partnership between amphiphysin and dynamin in clathrin-mediated endocytosis

Kohji Takei, Vladimir I. Slepnev, Volker Haucke et al. · Nature Cell Biology · 1999 · 653 citations

, , +14

Amphiphysin 2 (Bin1) and T-Tubule Biogenesis in Muscle

Eunkyung Lee, Melissa Marcucci, Laurie Daniell et al. · Science · 2002 · 466 citations

, , +17

Mutations in amphiphysin 2 (BIN1) disrupt interaction with dynamin 2 and cause autosomal recessive centronuclear myopathy

Anne-Sophie Nicot, Anne Toussaint, Valérie Tosch et al. · Nature Genetics · 2007 · 433 citations

, , +12

A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals.

Carol David, Peter S. McPherson, Olaf Mundigl et al. · Proceedings of the National Academy of Sciences · 1996 · 411 citations · Full text

, , +13

The SH3 Domain of Amphiphysin Binds the Proline-rich Domain of Dynamin at a Single Site That Defines a New SH3 Binding Consensus Sequence

Detlev Grabs, Vladimir I. Slepnev, Zhou Songyang et al. · Journal of Biological Chemistry · 1997 · 269 citations · Full text

, , +14

1–5 of 74

Authors

386

  1. PD
    Pietro De Camilli

    Yale University, United States

    10 publications · 2.5K citations

    10

    h-index

  2. KT
    Kohji Takei

    Okayama University, Japan

    8 publications · 986 citations

    8

    h-index

  3. JL
    Jocelyn Laporte

    Inserm, France

    7 publications · 988 citations

    7

    h-index

  4. VI
    Vladimir I. Slepnev

    Yale University, United States

    6 publications · 1.3K citations

    6

    h-index

  5. PS
    Peter S. McPherson

    Montreal Neurological Institute and Hospital, Canada

    6 publications · 961 citations

    6

    h-index

1–5 of 386

Institutions

151

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    12 h-index

    60 publications

    15.1K citations

  2. Yale University

    New Haven, United States

    11 h-index

    51 publications

    13.2K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    66 publications

    7.6K citations

  4. Inserm

    Paris, France

    9 h-index

    66 publications

    7.6K citations

  5. Université de Strasbourg

    Strasbourg, France

    7 h-index

    45 publications

    5.7K citations

  6. Institut de génétique et de biologie moléculaire et cellulaire

    Illkirch-Graffenstaden, France

    7 h-index

    45 publications

    6.2K citations

  7. Okayama University

    Okayama, Japan

    7 h-index

    54 publications

    2.8K citations

  8. Montreal Neurological Institute and Hospital

    Montreal, Canada

    5 h-index

    20 publications

    2.3K citations

1–8 of 151

Venues

  1. Journal of Biological Chemistry

    JBC · 12 publications · 1.2K citations

    12

    h-index

  2. The EMBO Journal

    4 publications · 525 citations

    4

    h-index

  3. Journal of Neurochemistry

    JNC · 3 publications · 140 citations

    3

    h-index

  4. Molecular Biology of the Cell

    MBC · 3 publications · 83 citations

    3

    h-index

  5. Traffic

    3 publications · 182 citations

    3

    h-index

1–5