Concepedia

Allosteric Conformation

Allosteric Conformation is a structural state of a protein characterized by a functional change in shape induced at one site due to the binding of a ligand at a distinct, spatially separated site, thereby modulating the protein's activity through conformational transmission.

116

Publications

6K

Citations

532

Authors

202

Institutions

Publications per year

2017–2026

24

Parents

Publications

116

Allosteric initiation and regulation of catalysis with a molecular knot

Vanesa Marcos, Alexander J. Stephens, Javier Jaramillo-García et al. · Science · 2016 · 254 citations · Full text

, , +9

Conformational spread in a ring of proteins: a stochastic approach to allostery

Thomas Duke, Nicolas Le Novère, D. Bray · Journal of Molecular Biology · 2001 · 238 citations

, , +14

Allosteric Control of RNA Polymerase by a Site That Contacts Nascent RNA Hairpins

Innokenti Toulokhonov, Irina Artsimovitch, Robert Landick · Science · 2001 · 222 citations

, , +16

Allosteric Changes in Protein Structure Computed by a Simple Mechanical Model: Hemoglobin T↔R2 Transition

Chunyan Xu, Dror Tobi, İvet Bahar · Journal of Molecular Biology · 2003 · 200 citations

, , +16

Molecular glue CELMoD compounds are regulators of cereblon conformation

Edmond R. Watson, Scott J. Novick, Mary E. Matyskiela et al. · Science · 2022 · 197 citations · Full text

, , +16

1–5 of 116

Authors

532

  1. GM
    Giuseppe Melacini

    McMaster University, Canada

    3 publications · 150 citations

    3

    h-index

  2. HK
    H. K. Schachman

    University of California, Berkeley, United States

    2 publications · 73 citations

    2

    h-index

  3. NP
    Nicola Pozzi

    Saint Louis University, United States

    2 publications · 95 citations

    2

    h-index

  4. TO
    Takehiro Ohta

    University of Hyogo, Japan

    2 publications · 38 citations

    2

    h-index

  5. BD
    Brian D. Zoltowski

    Southern Methodist University, United States

    2 publications · 88 citations

    2

    h-index

1–5 of 532

Institutions

202

  1. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    32 publications

    1K citations

  2. Institut Pasteur

    Paris, France

    4 h-index

    20 publications

    939 citations

  3. Inserm

    Paris, France

    4 h-index

    7 publications

    553 citations

  4. University of Washington

    Seattle, United States

    4 h-index

    24 publications

    707 citations

  5. Chinese Academy of Sciences

    Beijing, China

    4 h-index

    16 publications

    686 citations

  6. University of Cambridge

    Cambridge, United Kingdom

    3 h-index

    5 publications

    672 citations

  7. McMaster University

    Hamilton, Canada

    3 h-index

    7 publications

    271 citations

  8. Harvard University

    Cambridge, United States

    3 h-index

    23 publications

    2.1K citations

1–8 of 202

Venues

  1. Biochemistry

    16 publications · 645 citations

    14

    h-index

  2. Journal of Biological Chemistry

    JBC · 11 publications · 542 citations

    11

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 10 publications · 626 citations

    10

    h-index

  4. Journal of Molecular Biology

    JMB · 6 publications · 744 citations

    6

    h-index

  5. Biophysical Journal

    5 publications · 276 citations

    5

    h-index

1–5