Concepedia

Allosteric Biosensor Engineering

Allosteric Biosensor Engineering is a methodology in synthetic biology that involves the design and construction of biomolecular sensors wherein ligand-induced conformational changes at an allosteric site modulate the activity or signal output of a reporter domain, enabling real-time detection of specific analytes through engineered allosteric protein architectures.

20

Publications

1.1K

Citations

91

Authors

52

Institutions

Publications per year

2017–2026

15

Parents

Publications

20

The rational design of allosteric interactions in a monomeric protein and its applications to the construction of biosensors

Jonathan S. Marvin, Elizabeth Corcoran, N. A. Hattangadi et al. · Proceedings of the National Academy of Sciences · 1997 · 188 citations

, , +17

Evolution-guided engineering of small-molecule biosensors

Tim Snoek, Evan Kirk Chaberski, Francesca Ambri et al. · Nucleic Acids Research · 2019 · 139 citations · Full text

, , +15

Design of generic biosensors based on green fluorescent proteins with allosteric sites by directed evolution

Nobuhide Doi, Hiroshi Yanagawa · FEBS Letters · 1999 · 117 citations

, , +17

Directed evolution of the PcaV allosteric transcription factor to generate a biosensor for aromatic aldehydes

Leopoldo F. M. Machado, Andrew Currin, Neil Dixon · Journal of Biological Engineering · 2019 · 76 citations · Full text

, , +17

A Programmable DNAzyme for the Sensitive Detection of Nucleic Acids

Chenzhi Shi, Donglei Yang, Xiaowei Ma et al. · Angewandte Chemie International Edition · 2024 · 76 citations

, , +17

1–5 of 20

Authors

91

  1. ZG
    Zhong Guo

    The University of Queensland, Australia

    4 publications · 137 citations

    4

    h-index

  2. KA
    Kirill Alexandrov

    The University of Queensland, Australia

    4 publications · 137 citations

    4

    h-index

  3. WA
    Wayne A. Johnston

    The University of Queensland, Australia

    3 publications · 125 citations

    3

    h-index

  4. SE
    Selvakumar Edwardraja

    Pusan National University, South Korea

    3 publications · 125 citations

    3

    h-index

  5. PW
    Patricia Walden

    The University of Queensland, Australia

    3 publications · 125 citations

    3

    h-index

1–5 of 91

Institutions

52

  1. Queensland University of Technology

    Brisbane, Australia

    4 h-index

    16 publications

    628 citations

  2. ARC Centre of Excellence in Synthetic Biology

    Sydney, Australia

    4 h-index

    19 publications

    734 citations

  3. Commonwealth Scientific and Industrial Research Organisation

    Canberra, Australia

    3 h-index

    14 publications

    534 citations

  4. The University of Queensland

    Brisbane, Australia

    3 h-index

    12 publications

    548 citations

  5. University of Manchester

    Manchester, United Kingdom

    2 h-index

    4 publications

    267 citations

  6. Princeton University

    Princeton, United States

    2 h-index

    4 publications

    50 citations

  7. Novo Nordisk Foundation

    Copenhagen, Denmark

    2 h-index

    16 publications

    1.2K citations

  8. Shenzhen Institutes of Advanced Technology

    Shenzhen, China

    2 h-index

    2 publications

    151 citations

1–8 of 52

Venues

  1. Nucleic Acids Research

    3 publications · 193 citations

    3

    h-index

  2. ACS Synthetic Biology

    3 publications · 86 citations

    3

    h-index

  3. Nature Communications

    2 publications · 106 citations

    2

    h-index

  4. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 1 publications · 12 citations

    1

    h-index

  5. Angewandte Chemie International Edition

    1 publications · 76 citations

    1

    h-index

1–5