Patricia Walden

Dissecting Specificity in the Janus Kinases: The Structures of JAK-Specific Inhibitors Complexed to the JAK1 and JAK2 Protein Tyrosine Kinase Domains

Neal K. Williams, Rebecca S. Bamert, Onisha Patel et al. · Journal of Molecular Biology · 2009 · 265 citations

Protein Function, Signal Transduction, Jak-specific Inhibitors Complexed +10

Generalizable Protein Biosensors Based on Synthetic Switch Modules

Zhong Guo, Wayne A. Johnston, Jason Whitfield et al. · Journal of the American Chemical Society · 2019 · 61 citations

Engineering, Biomolecular Tool, Peptide Engineering +17

Engineering and exploiting synthetic allostery of NanoLuc luciferase

Zhong Guo, Rinky Parakra, Ying Xiong et al. · Nature Communications · 2022 · 36 citations · Full text

Engineering, Protein Assembly, Circular Permutation +17

Rv2969c, essential for optimal growth in<i>Mycobacterium tuberculosis</i>, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases

Lakshmanane Premkumar, Begoña Heras, Wilko Duprez et al. · Acta Crystallographica Section D Biological Crystallography · 2013 · 34 citations · Full text

Dsba-like Enzyme, Protein Assembly, Biomolecular Structure Prediction +18

Circular Permutated PQQ‐Glucose Dehydrogenase as an Ultrasensitive Electrochemical Biosensor

Zhong Guo, Oleh Smutok, Wayne A. Johnston et al. · Angewandte Chemie International Edition · 2021 · 26 citations