Concepedia

Allosteric Biosensor Design

Allosteric Biosensor Design is a computational and experimental framework that integrates protein engineering with signal transduction principles to create biomolecular sensors in which ligand-induced allosteric regulation modulates a measurable output signal through conformational coupling between an evolved sensory domain and a reporter domain.

28

Publications

1.4K

Citations

145

Authors

66

Institutions

Publications per year

2017–2026

20

Parents

Publications

28

The rational design of allosteric interactions in a monomeric protein and its applications to the construction of biosensors

Jonathan S. Marvin, Elizabeth Corcoran, N. A. Hattangadi et al. · Proceedings of the National Academy of Sciences · 1997 · 188 citations

, , +17

Evolution-guided engineering of small-molecule biosensors

Tim Snoek, Evan Kirk Chaberski, Francesca Ambri et al. · Nucleic Acids Research · 2019 · 139 citations · Full text

, , +15

Rapid construction of metabolite biosensors using domain-insertion profiling

Dana C. Nadler, Stacy-Anne Morgan, Avi I. Flamholz et al. · Nature Communications · 2016 · 131 citations · Full text

, , +17

Design of generic biosensors based on green fluorescent proteins with allosteric sites by directed evolution

Nobuhide Doi, Hiroshi Yanagawa · FEBS Letters · 1999 · 117 citations

, , +17

Revealing the Activity of Trimeric G-proteins in Live Cells with a Versatile Biosensor Design

Marcin Maziarz, Jong‐Chan Park, Anthony Leyme et al. · Cell · 2020 · 99 citations · Full text

, , +16

1–5 of 28

Authors

145

  1. MK
    Michael K. Jensen

    Rensselaer Polytechnic Institute, United States

    3 publications · 190 citations

    3

    h-index

  2. ZG
    Zhong Guo

    The University of Queensland, Australia

    3 publications · 73 citations

    3

    h-index

  3. KA
    Kirill Alexandrov

    The University of Queensland, Australia

    3 publications · 73 citations

    3

    h-index

  4. JD
    Jay D. Keasling

    University of California, Berkeley, United States

    3 publications · 190 citations

    3

    h-index

  5. FA
    Francesca Ambri

    Novo Nordisk Foundation, Denmark

    3 publications · 190 citations

    3

    h-index

1–5 of 145

Institutions

66

  1. University of California, Berkeley

    Berkeley, United States

    4 h-index

    8 publications

    845 citations

  2. Lawrence Berkeley National Laboratory

    Berkeley, United States

    3 h-index

    3 publications

    190 citations

  3. ARC Centre of Excellence in Synthetic Biology

    Sydney, Australia

    3 h-index

    13 publications

    350 citations

  4. Novo Nordisk Foundation

    Copenhagen, Denmark

    3 h-index

    24 publications

    1.5K citations

  5. Shenzhen Institutes of Advanced Technology

    Shenzhen, China

    3 h-index

    3 publications

    190 citations

  6. Shanghai Jiao Tong University

    Shanghai, China

    3 h-index

    10 publications

    646 citations

  7. Technical University of Denmark

    Kongens Lyngby, Denmark

    3 h-index

    24 publications

    1.5K citations

  8. Joint BioEnergy Institute

    Emeryville, United States

    3 h-index

    7 publications

    492 citations

1–8 of 66

Venues

  1. Biosensors and Bioelectronics

    4 publications · 98 citations

    4

    h-index

  2. Nucleic Acids Research

    3 publications · 193 citations

    3

    h-index

  3. Chemical Communications

    ChemComm · 3 publications · 84 citations

    3

    h-index

  4. Nature Communications

    3 publications · 237 citations

    3

    h-index

  5. ACS Synthetic Biology

    2 publications · 60 citations

    2

    h-index

1–5