Concepedia

Allelic Fraction Quantification

Allelic Fraction Quantification is a quantitative metric in liquid biopsy genetics that measures the proportion of a specific mutant allele relative to the total allelic content at a given genomic locus in cell-free DNA.

19

Publications

765

Citations

194

Authors

89

Institutions

Publications per year

2017–2026

14

Variants

VafVariant Allele Frequency

Parents

Publications

19

Gefitinib Plus Chemotherapy Versus Chemotherapy in Epidermal Growth Factor Receptor Mutation–Positive Non–Small-Cell Lung Cancer Resistant to First-Line Gefitinib (IMPRESS): Overall Survival and Biomarker Analyses

Tony Mok, Sang‐We Kim, Yi‐Long Wu et al. · Journal of Clinical Oncology · 2017 · 187 citations

, , +17

A clinical survey of mosaic single nucleotide variants in disease-causing genes detected by exome sequencing

Ye Cao, Mari Tokita, Edward S. Chen et al. · Genome Medicine · 2019 · 75 citations · Full text

, , +17

Comparative value of post-remission treatment in cytogenetically normal AML subclassified by NPM1 and FLT3-ITD allelic ratio

Jurjen Versluis, Florentien E. M. in ’t Hout, Raynier Devillier et al. · Leukemia · 2016 · 65 citations · Full text

, , +10

Accurately Identifying Low-Allelic Fraction Variants in Single Samples with Next-Generation Sequencing: Applications in Tumor Subclone Resolution

Lucy F. Stead, Kate Sutton, Graham R. Taylor et al. · Human Mutation · 2013 · 58 citations

, , +17

Confirming putative variants at ≤ 5% allele frequency using allele enrichment and Sanger sequencing

Yan Helen Yan, Sherry X. Chen, Lauren Y. Cheng et al. · Scientific Reports · 2021 · 48 citations · Full text

, , +17

1–5 of 19

Authors

194

  1. KA
    Kenji Amemiya

    Yamanashi Prefectural Central Hospital, Japan

    2 publications · 44 citations

    2

    h-index

  2. YH
    Yosuke Hirotsu

    Yamanashi Prefectural Central Hospital, Japan

    2 publications · 44 citations

    2

    h-index

  3. MO
    Masao Omata

    The University of Tokyo, Japan

    2 publications · 44 citations

    2

    h-index

  4. HM
    Hitoshi Mochizuki

    Yamanashi Prefectural Central Hospital, Japan

    2 publications · 44 citations

    2

    h-index

  5. TC
    Tiansheng Chen

    The University of Texas Medical Branch at Galveston, United States

    1 publications · 75 citations

    1

    h-index

1–5 of 194

Institutions

89

  1. Radboud University Medical Center

    Nijmegen, The Netherlands

    2 h-index

    4 publications

    214 citations

  2. Radboud University Nijmegen

    Nijmegen, The Netherlands

    2 h-index

    4 publications

    214 citations

  3. Rice University

    Houston, United States

    2 h-index

    4 publications

    219 citations

  4. Amsterdam UMC Location University of Amsterdam

    Amsterdam, The Netherlands

    2 h-index

    3 publications

    103 citations

  5. Chinese University of Hong Kong

    Hong Kong, Hong Kong

    2 h-index

    17 publications

    3.1K citations

  6. Leiden University Medical Center

    Leiden, The Netherlands

    2 h-index

    12 publications

    274 citations

  7. Yamanashi Prefectural Central Hospital

    Kofu, Japan

    2 h-index

    14 publications

    284 citations

  8. Mayo Clinic in Arizona

    Scottsdale, United States

    1 h-index

    1 publications

    20 citations

1–8 of 89

Venues

  1. Scientific Reports

    2 publications · 71 citations

    2

    h-index

  2. PLoS ONE

    2 publications · 56 citations

    2

    h-index

  3. Bioinformatics

    2 publications · 47 citations

    2

    h-index

  4. American Journal of Case Reports

    1 publications · 10 citations

    1

    h-index

  5. BMC Genomics

    1 publications · 34 citations

    1

    h-index

1–5