Concepedia

Aggregation-prone Intermediates

Aggregation-Prone Intermediates is a folding intermediate characterized by exposed hydrophobic regions and partial structural disorder that predispose it to self-associate into non-native, insoluble aggregates rather than progressing to the native conformation.

116

Publications

6.5K

Citations

520

Authors

217

Institutions

Publications per year

2017–2026

39

Parents

Publications

116

Mechanisms of Protein Stabilization and Prevention of Protein Aggregation by Glycerol

Vincent Vagenende, Miranda G.S. Yap, Bernhardt L. Trout · Biochemistry · 2009 · 526 citations

, , +17

Prediction of Aggregation-Prone Regions in Structured Proteins

Gian Gaetano Tartaglia, Amol Pawar, Silvia Campioni et al. · Journal of Molecular Biology · 2008 · 438 citations

, , +14

A role for Q/N-rich aggregation-prone regions in P-body localization

Martin A.M. Reijns, Ross D. Alexander, Michael P. Spiller et al. · Journal of Cell Science · 2008 · 219 citations · Full text

, , +11

Dissection and Design of Yeast Prions

Lev Osherovich, Brian S. Cox, Mick F. Tuite et al. · PLoS Biology · 2004 · 189 citations · Full text

, , +17

Aggregation of Bovine Insulin Probed by DSC/PPC Calorimetry and FTIR Spectroscopy

Wojciech Dzwolak, Revanur Ravindra, Julia Lendermann et al. · Biochemistry · 2003 · 178 citations

, , +17

1–5 of 116

Authors

520

  1. JK
    Jonathan King

    Massachusetts Institute of Technology, United States

    5 publications · 313 citations

    5

    h-index

  2. FC
    Fabrizio Chiti

    University of Florence, Italy

    3 publications · 519 citations

    3

    h-index

  3. AD
    Alfonso De Simone

    Imperial College London, United Kingdom

    3 publications · 230 citations

    3

    h-index

  4. SD
    Scott D. Betts

    University of Michigan, United States

    2 publications · 59 citations

    2

    h-index

  5. AN
    Antonino Natalello

    University of Milano-Bicocca, Italy

    2 publications · 98 citations

    2

    h-index

1–5 of 520

Institutions

217

  1. University of Cambridge

    Cambridge, United Kingdom

    7 h-index

    27 publications

    3.4K citations

  2. Massachusetts Institute of Technology

    Cambridge, United States

    7 h-index

    13 publications

    1.2K citations

  3. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    3 h-index

    5 publications

    444 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    10 publications

    666 citations

  5. Boston University

    Boston, United States

    3 h-index

    11 publications

    399 citations

  6. University of Florence

    Florence, Italy

    3 h-index

    6 publications

    1.1K citations

  7. National University of Singapore

    Singapore, Singapore

    3 h-index

    8 publications

    1.9K citations

  8. Universitat Autònoma de Barcelona

    Cerdanyola del Vallès, Spain

    3 h-index

    12 publications

    236 citations

1–8 of 217

Venues

  1. Protein Science

    PS · 9 publications · 545 citations

    9

    h-index

  2. Journal of Molecular Biology

    JMB · 9 publications · 864 citations

    9

    h-index

  3. Scientific Reports

    6 publications · 147 citations

    6

    h-index

  4. Biochemistry

    6 publications · 804 citations

    6

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 350 citations

    6

    h-index

1–5