Concepedia

Aggregation Resistance Engineering

Aggregation Resistance Engineering is a protein engineering strategy that specifically targets the suppression of non-specific intermolecular interactions on enzyme surfaces to enhance solubility and stability without compromising catalytic function.

13

Publications

829

Citations

82

Authors

38

Institutions

Publications per year

2017–2026

5

Parents

Publications

13

General strategy for the generation of human antibody variable domains with increased aggregation resistance

Kip Dudgeon, Romain Rouet, Iris Kokmeijer et al. · Proceedings of the National Academy of Sciences · 2012 · 191 citations · Full text

, , +17

Solvation-assisted Pressure Tuning of Insulin Fibrillation: From Novel Aggregation Pathways to Biotechnological Applications

Stefan Grudzielanek, Vytautas Smirnovas, Roland Winter · Journal of Molecular Biology · 2005 · 111 citations

, , +15

Rational Design of Solution Additives for the Prevention of Protein Aggregation

Brian M. Baynes, Bernhardt L. Trout · Biophysical Journal · 2004 · 111 citations · Full text

, , +12

Thermodynamically Stable Aggregation-Resistant Antibody Domains through Directed Evolution

Kristoffer Famm, Lars Hansen, Daniel Christ et al. · Journal of Molecular Biology · 2008 · 109 citations

, , +14

Planar AIEgens with Enhanced Solid‐State Luminescence and ROS Generation for Multidrug‐Resistant Bacteria Treatment

Jen‐Shyang Ni, Tianliang Min, Yaxi Li et al. · Angewandte Chemie International Edition · 2020 · 103 citations

, , +14

1–5 of 13

Authors

82

  1. DC
    Daniel Christ

    Garvan Institute of Medical Research, Australia

    2 publications · 300 citations

    2

    h-index

  2. FC
    Fabrizio Chiti

    University of Florence, Italy

    1 publications · 15 citations

    1

    h-index

  3. AP
    Andreas Plückthun

    University of Zurich, Switzerland

    1 publications · 49 citations

    1

    h-index

  4. JN
    Jen‐Shyang Ni

    National Central University, Taiwan

    1 publications · 103 citations

    1

    h-index

  5. CL
    Chun Loong Ho

    Southern University of Science and Technology, China

    1 publications · 103 citations

    1

    h-index

1–5 of 82

Institutions

38

  1. Chinese Academy of Sciences

    Beijing, China

    2 h-index

    2 publications

    120 citations

  2. Garvan Institute of Medical Research

    Darlinghurst, Australia

    2 h-index

    8 publications

    1.4K citations

  3. Tulane University

    New Orleans, United States

    1 h-index

    1 publications

    23 citations

  4. UNSW Sydney

    Sydney, Australia

    1 h-index

    4 publications

    764 citations

  5. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    1 h-index

    2 publications

    218 citations

  6. Victor Chang Cardiac Research Institute

    Sydney, Australia

    1 h-index

    3 publications

    573 citations

  7. University of Florence

    Florence, Italy

    1 h-index

    2 publications

    30 citations

  8. Universidad Nacional de La Plata

    La Plata, Argentina

    1 h-index

    1 publications

    16 citations

1–8 of 38

Venues

  1. Journal of Molecular Biology

    JMB · 3 publications · 269 citations

    3

    h-index

  2. Journal of Colloid and Interface Science

    2 publications · 35 citations

    2

    h-index

  3. Journal of the American Chemical Society

    JACS · 1 publications · 26 citations

    1

    h-index

  4. FEBS Journal

    1 publications · 15 citations

    1

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 191 citations

    1

    h-index

1–5