Concepedia

Aggregate Genetic Effects

Aggregate Genetic Effects is a theoretical construct in genetic epidemiology that refers to the cumulative influence of multiple genetic variants within a family or population on the phenotypic expression of a trait or disease, distinguishing it from individual gene effects by emphasizing the collective burden of inherited genetic factors.

65

Publications

4K

Citations

635

Authors

212

Institutions

Publications per year

2017–2026

15

Parents

Publications

65

Correlations between apolipoprotein E ε4 gene dose and brain-imaging measurements of regional hypometabolism

Eric M. Reiman, Kewei Chen, Gene E. Alexander et al. · Proceedings of the National Academy of Sciences · 2005 · 398 citations

, , +17

Major Depressive Disorder in a Community-Based Twin Sample: Are There Different Genetic and Environmental Contributions for Men and Women?

L. J. Bierut · Archives of General Psychiatry · 1999 · 253 citations

, , +15

Heritability of Bronchopulmonary Dysplasia, Defined According to the Consensus Statement of the National Institutes of Health

Pascal M. Lavoie, Chandra Pham, Kerry L. Jang · PEDIATRICS · 2008 · 240 citations

, , +16

What do Twins Studies Reveal About the Economic Returns to Education? A Comparison of Australian and US Findings

Paul W. Miller, Charles Mulvey, Nicholas G. Martin · UWA Profiles and Research Repository (University of Western Australia) · 1995 · 227 citations

, , +15

Polygenic risk of Alzheimer disease is associated with early- and late-life processes

Elizabeth C. Mormino, Reisa A. Sperling, Avram J. Holmes et al. · Neurology · 2016 · 196 citations · Full text

, , +17

1–5 of 65

Authors

635

  1. DM
    Danielle M. Dick

    Virginia Commonwealth University, United States

    5 publications · 180 citations

    5

    h-index

  2. JK
    Jaakko Kaprio

    University of Helsinki, Finland

    4 publications · 303 citations

    4

    h-index

  3. AC
    Alexis C. Edwards

    Virginia Commonwealth University, United States

    4 publications · 170 citations

    4

    h-index

  4. KS
    Kenneth S. Kendler

    Virginia Commonwealth University, United States

    4 publications · 246 citations

    4

    h-index

  5. BT
    Bradley T. Webb

    Virginia Commonwealth University, United States

    4 publications · 183 citations

    4

    h-index

1–5 of 635

Institutions

212

  1. Virginia Commonwealth University

    Richmond, United States

    9 h-index

    45 publications

    2K citations

  2. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    6 h-index

    28 publications

    1.1K citations

  3. Washington University in St. Louis

    St Louis, United States

    4 h-index

    6 publications

    404 citations

  4. Brown University

    Providence, United States

    4 h-index

    17 publications

    1K citations

  5. University of Helsinki

    Helsinki, Finland

    4 h-index

    15 publications

    1.2K citations

  6. University of Bristol

    Bristol, United Kingdom

    4 h-index

    11 publications

    694 citations

  7. Karolinska Institutet

    Stockholm, Sweden

    4 h-index

    21 publications

    1.3K citations

  8. University of Colorado Boulder

    Boulder, United States

    3 h-index

    6 publications

    413 citations

1–8 of 212

Venues

  1. Genetic Epidemiology

    4 publications · 131 citations

    4

    h-index

  2. BMC Proceedings

    3 publications · 61 citations

    3

    h-index

  3. Genetics

    2 publications · 85 citations

    2

    h-index

  4. Forest Ecology and Management

    2 publications · 36 citations

    2

    h-index

  5. PLoS ONE

    2 publications · 41 citations

    2

    h-index

1–5