Concepedia

Adme Profiling

ADME Profiling is a systematic assessment method in drug discovery that characterizes the absorption, distribution, metabolism, and excretion properties of bioactive compounds to evaluate their pharmacokinetic behavior and potential for in vivo efficacy.

583

Publications

23.8K

Citations

3.8K

Authors

981

Institutions

Publications per year

2017–2026

386

Variants

Adme Characterization

Parents

Publications

583

ADMET-score – a comprehensive scoring function for evaluation of chemical drug-likeness

Longfei Guan, Hongbin Yang, Yingchun Cai et al. · MedChemComm · 2018 · 694 citations

, , +16

Discovery of Dapagliflozin: A Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

Wei Meng, Bruce A. Ellsworth, Alexandra A. Nirschl et al. · Journal of Medicinal Chemistry · 2008 · 628 citations · Full text

, , +17

Screening for human ADME/Tox drug properties in drug discovery

Albert P. Li · Drug Discovery Today · 2001 · 538 citations

, , +9

Estimation of ADME Properties with Substructure Pattern Recognition

Jie Shen, Feixiong Cheng, You Xu et al. · Journal of Chemical Information and Modeling · 2010 · 353 citations

, , +15

New and Original p<i>K</i><sub>a</sub> Prediction Method Using Grid Molecular Interaction Fields

Francesca Milletti, Loriano Storchi, Gianluca Sforna et al. · Journal of Chemical Information and Modeling · 2007 · 317 citations

, , +17

1–5 of 583

Authors

3.8K

  1. TH
    Tingjun Hou

    Zhejiang University, China

    7 publications · 1.2K citations

    7

    h-index

  2. HŞ
    Halil Şenol

    Bezmiâlem Vakıf Üniversitesi, Türkiye

    5 publications · 228 citations

    6

    h-index

  3. BT
    Burak Tüzün

    Sivas Cumhuriyet Üniversitesi, Türkiye

    6 publications · 158 citations

    6

    h-index

  4. BN
    Begüm Nurpelin Sağlık

    Anadolu University, Türkiye

    5 publications · 140 citations

    5

    h-index

  5. CZ
    Claudio Zamperini

    University of Siena, Italy

    5 publications · 190 citations

    5

    h-index

1–5 of 3.8K

Institutions

981

  1. King Saud University

    Riyadh, Saudi Arabia

    11 h-index

    32 publications

    858 citations

  2. Novartis (Switzerland)

    Basel, Switzerland

    10 h-index

    52 publications

    3.1K citations

  3. Pfizer (United States)

    New York, United States

    10 h-index

    113 publications

    8.2K citations

  4. Cairo University

    Giza, Egypt

    9 h-index

    16 publications

    385 citations

  5. Chinese Academy of Medical Sciences & Peking Union Medical College

    Beijing, China

    8 h-index

    61 publications

    1.8K citations

  6. Savitribai Phule Pune University

    Pune, India

    8 h-index

    19 publications

    377 citations

  7. Erciyes University

    Kayseri, Türkiye

    7 h-index

    11 publications

    283 citations

  8. GlaxoSmithKline (United Kingdom)

    London, United Kingdom

    7 h-index

    47 publications

    1K citations

1–8 of 981

Venues

  1. Journal of Medicinal Chemistry

    51 publications · 3.1K citations

    33

    h-index

  2. Journal of Molecular Structure

    20 publications · 549 citations

    16

    h-index

  3. Molecules

    12 publications · 392 citations

    12

    h-index

  4. Bioorganic Chemistry

    10 publications · 461 citations

    11

    h-index

  5. Frontiers in Pharmacology

    7 publications · 235 citations

    10

    h-index

1–5