Concepedia

Adhesion Complex Disassembly

Adhesion Complex Disassembly is a molecular process in cell biology whereby integrin-mediated adhesion structures at the cell membrane are systematically dismantled through the coordinated dissociation of structural and signaling proteins, enabling cell detachment and migration.

38

Publications

5.7K

Citations

192

Authors

74

Institutions

Publications per year

2017–2026

4

Parents

Publications

38

FAK–Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

Donna J. Webb, Karen Donais, Leanna Whitmore et al. · Nature Cell Biology · 2004 · 1.4K citations

, , +12

Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly

Edward R. Horton, Adam Byron, Janet A. Askari et al. · Nature Cell Biology · 2015 · 568 citations · Full text

, , +14

Differential Dynamics of α5 Integrin, Paxillin, and α-Actinin during Formation and Disassembly of Adhesions in Migrating Cells

Christina M. Laukaitis, Donna J. Webb, Karen Donais et al. · The Journal of Cell Biology · 2001 · 451 citations · Full text

, , +17

Coupling of PAK-Interacting Exchange Factor PIX to GIT1 Promotes Focal Complex Disassembly

Zhou-shen Zhao, Edward Manser, Tsui-Han Loo et al. · Molecular and Cellular Biology · 2000 · 362 citations

, , +13

Spatial mapping of integrin interactions and dynamics during cell migration by Image Correlation Microscopy

Paul W. Wiseman, Claire M. Brown, Donna J. Webb et al. · Journal of Cell Science · 2004 · 229 citations

, , +16

1–5 of 38

Authors

192

  1. DJ
    Donna J. Webb

    University of Virginia, United States

    3 publications · 2.1K citations

    3

    h-index

  2. AF
    Alan F. Horwitz

    University of Virginia, United States

    3 publications · 2.1K citations

    3

    h-index

  3. JK
    Jeannette Kunz

    Baylor College of Medicine, United States

    2 publications · 270 citations

    2

    h-index

  4. JA
    Janet A. Askari

    University of Manchester, United Kingdom

    2 publications · 728 citations

    2

    h-index

  5. VJ
    Valerie J. Fincham

    Cancer Research UK Scotland Institute, United Kingdom

    2 publications · 267 citations

    2

    h-index

1–5 of 192

Institutions

74

  1. University of Virginia

    Charlottesville, United States

    4 h-index

    14 publications

    9.3K citations

  2. Cornell University

    Ithaca, United States

    3 h-index

    9 publications

    1.4K citations

  3. Harvard University

    Cambridge, United States

    3 h-index

    5 publications

    1.6K citations

  4. Institute of Molecular and Cell Biology

    Singapore, Singapore

    2 h-index

    8 publications

    1.5K citations

  5. Karolinska Institutet

    Stockholm, Sweden

    2 h-index

    6 publications

    238 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    11 publications

    1.6K citations

  7. University of British Columbia

    Vancouver, Canada

    2 h-index

    4 publications

    150 citations

  8. McGill University

    Montreal, Canada

    2 h-index

    6 publications

    594 citations

1–8 of 74

Venues

  1. Nature Cell Biology

    NCB · 5 publications · 2.4K citations

    5

    h-index

  2. Journal of Cell Science

    5 publications · 379 citations

    5

    h-index

  3. Journal of Biological Chemistry

    JBC · 4 publications · 615 citations

    4

    h-index

  4. Molecular and Cellular Biology

    MCB · 3 publications · 439 citations

    3

    h-index

  5. Molecular Biology of the Cell

    MBC · 2 publications · 171 citations

    2

    h-index

1–5