Concepedia

Adaptive Platform Trials

Adaptive Platform Trial is a type of clinical trial design that belongs to the class of longitudinal studies evaluating multiple interventions within a single master protocol, distinguished by its structured adaptability to add or drop treatment arms, modify randomization probabilities, and share control groups over time based on interim Bayesian analyses.

45

Publications

2.5K

Citations

947

Authors

321

Institutions

Publications per year

2017–2026

41

Variants

Adaptive Platform Trial

Parents

Publications

45

The REMAP-CAP (Randomized Embedded Multifactorial Adaptive Platform for Community-acquired Pneumonia) Study. Rationale and Design

Derek C. Angus, Scott Berry, Roger Lewis et al. · Annals of the American Thoracic Society · 2020 · 445 citations · Full text

, , +17

Azithromycin for community treatment of suspected COVID-19 in people at increased risk of an adverse clinical course in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial

Christopher Butler, Jienchi Dorward, Ly‐Mee Yu et al. · The Lancet · 2021 · 318 citations · Full text

, , +12

Efficiencies of platform clinical trials: A vision of the future

Benjamin R. Saville, Scott Berry · Clinical Trials · 2016 · 316 citations

, , +14

CIRCULATE‐Japan: Circulating tumor DNA–guided adaptive platform trials to refine adjuvant therapy for colorectal cancer

Hiroya Taniguchi, Yoshiaki Nakamura, Daisuke Kotani et al. · Cancer Science · 2021 · 143 citations · Full text

, , +17

Assessment of Residual Cancer Burden and Event-Free Survival in Neoadjuvant Treatment for High-risk Breast Cancer

W. Fraser Symmans, Christina Yau, Yunn-Yi Chen et al. · JAMA Oncology · 2021 · 106 citations · Full text

, , +16

1–5 of 45

Authors

947

  1. BR
    Benjamin R. Saville

    Vanderbilt University, United States

    8 publications · 836 citations

    8

    h-index

  2. MP
    Mahesh Parmar

    University College London, United Kingdom

    6 publications · 197 citations

    6

    h-index

  3. CB
    Christopher Butler

    University of Oxford, United Kingdom

    6 publications · 419 citations

    6

    h-index

  4. MA
    Michelle A. Detry

    Berry & Associates (United States), United States

    5 publications · 819 citations

    5

    h-index

  5. SB
    Scott Berry

    Berry & Associates (United States), United States

    6 publications · 876 citations

    5

    h-index

1–5 of 947

Institutions

321

  1. Berry & Associates (United States)

    Dexter, United States

    11 h-index

    37 publications

    4K citations

  2. University of Oxford

    Oxford, United Kingdom

    10 h-index

    89 publications

    7.2K citations

  3. University College London

    London, United Kingdom

    8 h-index

    72 publications

    2.8K citations

  4. Vanderbilt University

    Nashville, United States

    7 h-index

    9 publications

    471 citations

  5. Monash University

    Melbourne, Australia

    6 h-index

    21 publications

    4.5K citations

  6. University of California, San Francisco

    San Francisco, United States

    5 h-index

    24 publications

    1.5K citations

  7. The University of Texas MD Anderson Cancer Center

    Houston, United States

    5 h-index

    10 publications

    483 citations

  8. University of British Columbia

    Vancouver, Canada

    5 h-index

    9 publications

    604 citations

1–8 of 321

Venues

  1. Clinical Trials

    5 publications · 457 citations

    5

    h-index

  2. Trials

    4 publications · 180 citations

    4

    h-index

  3. BMJ Open

    2 publications · 55 citations

    2

    h-index

  4. Biometrics

    2 publications · 62 citations

    2

    h-index

  5. F1000Research

    2 publications · 35 citations

    2

    h-index

1–5