During 1911–1920, histopathology coalesced around a clinicopathological synthesis that anchored diagnoses in morphological criteria and tissue-based inference across organ systems. Neuropathology emerged as a central axis, with histology clarifying inflammatory and degenerative CNS conditions, brain tumors, and pseudotumoral processes. Dermatopathology and skin biology, oncopathology including bone and liver tumors, and patterns in gastrointestinal and hepatobiliary pathology expanded the field, foregrounding skin architecture, cancer biology, and liver-related lesions. Influential Works: Cross-period works shaped the era's trajectory: Pathologisch-anatomische Diagnostik (1917) introduced a morphology-based, autopsy-driven diagnostic framework that standardized histopathologic criteria and linked tissue changes to clinical inference. Pathologisch-anatomische Studien bei Frühgeborenen (1919) advanced perinatal pathology by detailing developmental histology and congenital or injury-related lesions in preterm infants, influencing neonatal pathology. Foundational texts extended ocular and oral mucosal histology, with Anatomie und Histologie des Menschlichen Augapfels (1912) and The normal and pathological histology of the mouth (1918) underpinning later ophthalmopathology and dental pathology.