Concepedia

4-Hydroxynonenal Formation

4-Hydroxynonenal Formation is a biochemical process involving the generation of 4-hydroxynonenal, a reactive aldehyde, through the peroxidation of omega-6 polyunsaturated fatty acids, particularly arachidonic or linoleic acid, under oxidative stress conditions.

85

Publications

7.2K

Citations

342

Authors

103

Institutions

Publications per year

2017–2026

3

Variants

4-Hne Formation

Parents

Publications

85

Four-Hydroxynonenal, a Product of Lipid Peroxidation, is Increased in the Brain in Alzheimer’s Disease

William R. Markesbery, Mark A. Lovell · Neurobiology of Aging · 1998 · 683 citations

, , +14

Covalent attachment of 4-hydroxynonenal to glyceraldehyde-3-phosphate dehydrogenase. A possible involvement of intra- and intermolecular cross-linking reaction.

Kôji Uchida, Earl R. Stadtman · Journal of Biological Chemistry · 1993 · 516 citations · Full text

, , +13

Elevated 4-Hydroxynonenal in Ventricular Fluid in Alzheimer’s Disease

Mark A. Lovell, W. D. Ehmann, Mark P. Mattson et al. · Neurobiology of Aging · 1997 · 409 citations

, , +14

Two Distinct Pathways of Formation of 4-Hydroxynonenal

Claus Schneider, Keri A. Tallman, Ned A. Porter et al. · Journal of Biological Chemistry · 2001 · 311 citations · Full text

, , +12

Reactions of <i>N</i>-Methyl-2-phenylindole with Malondialdehyde and 4-Hydroxyalkenals. Mechanistic Aspects of the Colorimetric Assay of Lipid Peroxidation

Irène Erdelmeier, Dominique Gérard-Monnier, Jean‐Claude Yadan et al. · Chemical Research in Toxicology · 1998 · 286 citations

, , +14

1–5 of 85

Authors

342

  1. TG
    Tilman Grune

    German Institute of Human Nutrition, Germany

    12 publications · 696 citations

    12

    h-index

  2. WG
    Werner G. Siems

    Stiftung Juliusspital, Germany

    11 publications · 597 citations

    11

    h-index

  3. HE
    Hermann Esterbauer

    University of Graz, Austria

    8 publications · 599 citations

    8

    h-index

  4. NA
    Ned A. Porter

    Vanderbilt University, United States

    5 publications · 556 citations

    5

    h-index

  5. HZ
    Helmward Zöllner

    University of Graz, Austria

    4 publications · 420 citations

    4

    h-index

1–5 of 342

Institutions

103

  1. University of Graz

    Graz, Austria

    11 h-index

    31 publications

    2.7K citations

  2. Humboldt-Universität zu Berlin

    Berlin, Germany

    9 h-index

    22 publications

    908 citations

  3. Charité - Universitätsmedizin Berlin

    Berlin, Germany

    8 h-index

    20 publications

    803 citations

  4. Vanderbilt University

    Nashville, United States

    7 h-index

    27 publications

    2.9K citations

  5. Stiftung Juliusspital

    Wurzburg, Germany

    7 h-index

    10 publications

    801 citations

  6. University of Colorado Health

    Aurora, United States

    4 h-index

    9 publications

    876 citations

  7. University of Kentucky

    Lexington, United States

    4 h-index

    12 publications

    3.7K citations

  8. The University of Texas Medical Branch at Galveston

    Galveston, United States

    3 h-index

    7 publications

    812 citations

1–8 of 103

Venues

  1. Free Radical Biology and Medicine

    11 publications · 552 citations

    11

    h-index

  2. Chemical Research in Toxicology

    5 publications · 555 citations

    5

    h-index

  3. Biochemical Journal

    BJ · 4 publications · 439 citations

    4

    h-index

  4. Journal of Biological Chemistry

    JBC · 4 publications · 899 citations

    4

    h-index

  5. Hepatology

    3 publications · 172 citations

    3

    h-index

1–5