Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit

Björn C. Schroeder, Tong Cheng, Yuh Nung Jan, +1

Cell

Signal TransductionMolecular PhysiologyExpression CloningMolecular BiologyIon Channels +5

Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective

Tong Cheng, Dong Liu, John H. Griffin, +5

Nature Medicine

GliomaMedicineProtein CApoptosisAutophagy +9

A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro.

Ikuo Inoue, Toshiaki Nakajima, Christopher S. Williams, +8

Journal of Clinical Investigation

HypertensionPromoter ActivityGeneticsAffects Basal TranscriptionGenetic Epidemiology +16

TMEM16F Forms a Ca2+-Activated Cation Channel Required for Lipid Scrambling in Platelets during Blood Coagulation

Huanghe Yang, Andrew Kim, Tovo David, +8

Cell

ThrombopoiesisThrombosisMolecular PhysiologySignal TransductionBlood Platelet +10

Studies on expression and function of the TMEM16A calcium-activated chloride channel

Fen Huang, Jason R. Rock, Brian D. Harfe, +4

Proceedings of the National Academy of Sciences

Protein SecretionSmooth Muscle ContractionCytoskeletonMechanotransductionCellular Physiology +16

Elements of a Paracrine Tubular Renin-Angiotensin System Along the Entire Nephron

Andreas Rohrwasser, Terry K. Morgan, Harrison F. Dillon, +9

Hypertension

Electron cryo-microscopy structure of the mechanotransduction channel NOMPC

Peng Jin, David Bulkley, Yanmeng Guo, +9

Nature

Mechanotransduction Channel NompcElectron MicroscopyMicroscopyCryogenicsElectron Microscope +3

1,25(OH)2 vitamin D3, and retinoic acid antagonize endothelin-stimulated hypertrophy of neonatal rat cardiac myocytes.

Jiangping Wu, Miklós Garami, Tong Cheng, +1

Journal of Clinical Investigation

Cardiac MuscleCardiomyopathyHeart FailureMolecular PhysiologyEndothelin Treatment +12

APC and GSK-3β Are Involved in mPar3 Targeting to the Nascent Axon and Establishment of Neuronal Polarity

Song‐Hai Shi, Tong Cheng, Lily Yeh Jan, +1

Current Biology

Nascent AxonDevelopmental BiologyMolecular NeuroscienceSynaptic TransmissionNeuroscience +8

Ankyrin Repeats Convey Force to Gate the NOMPC Mechanotransduction Channel

Wei Zhang, Li E. Cheng, Maike Kittelmann, +7

Cell

MechanotransductionNompc Mechanotransduction ChannelBiophysicsPhysics