Linyu Yang

Cevipabulin-tubulin complex reveals a novel agent binding site on α-tubulin with tubulin degradation effect

Jianhong Yang, Yamei Yu, Yong Li et al. · Science Advances · 2021 · 62 citations · Full text

Identification of Pyrrolo[2,3-<i>d</i>]pyrimidine-Based Derivatives as Potent and Orally Effective Fms-like Tyrosine Receptor Kinase 3 (FLT3) Inhibitors for Treating Acute Myelogenous Leukemia

Xue Yuan, Yong Chen, Wanhua Zhang et al. · Journal of Medicinal Chemistry · 2019 · 36 citations · Full text

Purinostat Mesylate Is a Uniquely Potent and Selective Inhibitor of HDACs for the Treatment of <i>BCR-ABL</i> –Induced B-Cell Acute Lymphoblastic Leukemia

Linyu Yang, Qiang Qiu, Minghai Tang et al. · Clinical Cancer Research · 2019 · 19 citations · Full text

Identification of a Novel 2,8-Diazaspiro[4.5]decan-1-one Derivative as a Potent and Selective Dual TYK2/JAK1 Inhibitor for the Treatment of Inflammatory Bowel Disease

Tao Yang, Xue Cui, Minghai Tang et al. · Journal of Medicinal Chemistry · 2022 · 18 citations · Full text

Discovery of a Series of Hydroxamic Acid-Based Microtubule Destabilizing Agents with Potent Antitumor Activity

Linyu Yang, Wanhua Zhang, Qiang Qiu et al. · Journal of Medicinal Chemistry · 2021 · 17 citations · Full text