AMP-Activated Protein Kinase (AMPK) Regulates Energy Metabolism through Modulating Thermogenesis in Adipose Tissue

Lingyan Wu, Lina Zhang, Bohan Li, +5

Frontiers in Physiology

Metabolic RemodelingCaloric RestrictionGlucose ToleranceOxidative StressObesity +23

Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans

Lingyan Wu, Mingfeng Xia, Yanan Duan, +10

Cell Death and Disease

ObesityMetabolic SyndromeInsulin SignalingBiochemistryPhysiology +13

The Landscape of Histone Modifications in a High-Fat Diet-Induced Obese (DIO) Mouse Model

Litong Nie, Lin Shuai, Mingrui Zhu, +5

Molecular & Cellular Proteomics

Histone ModificationsMetabolic DisorderHistone MarksFatty Liver DiseaseEpigenetics +19

Forrestiacids A and B, Pentaterpene Inhibitors of ACL and Lipogenesis: Extending the Limits of Computational NMR Methods in the Structure Assignment of Complex Natural Products

Juan Xiong, Peng‐Jun Zhou, Haowen Jiang, +11

Angewandte Chemie International Edition

Azoxystrobin, a mitochondrial complex III Qo site inhibitor, exerts beneficial metabolic effects in vivo and in vitro

Anhui Gao, Yanyun Fu, Kunzhi Zhang, +6

Biochimica et Biophysica Acta (BBA) - General Subjects

Beneficial Metabolic EffectsMitochondrial FunctionBiochemistryMedicineReactive Oxygen Specie +3

The triterpenoid sapogenin (2α-OH-Protopanoxadiol) ameliorates metabolic syndrome via the intestinal FXR/GLP-1 axis through gut microbiota remodelling

Zhifu Xie, Haowen Jiang, Wei Liu, +11

Cell Death and Disease

DysbiosisTriterpenoid SapogeninGp2 TreatmentGastrointestinal PharmacologyGut Microbiota +18

Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice

Yanyan Yu, Shichao Cui, Tian-nan Zheng, +8

Acta Pharmacologica Sinica

Insulin ResistanceMetabolic SyndromeObesityInflammationMetabolic Disorder +13

Identification and structural insight of an effective PPARγ modulator with improved therapeutic index for anti-diabetic drug discovery

Haowen Jiang, X. Edward Zhou, Jingjing Shi, +13

Chemical Science

Association between Metabolic Dysfunction-associated Fatty Liver Disease and Cognitive Impairment

Qiang Yu, Ruixin He, Haowen Jiang, +9

Journal of Clinical and Translational Hepatology

AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models

Shui-mei Sun, Zhifu Xie, Yangming Zhang, +10

Acta Pharmacologica Sinica

InflammationMetabolic SyndromeBiochemistryMedicineLiver Physiology +6