Andrographolide reversed 5-FU resistance in human colorectal cancer by elevating BAX expression

Weicheng Wang, Wenjie Guo, Lele Li, +7

Biochemical Pharmacology

Tumor BiologyMedicinePharmacologyColorectal CancerPathology +6

Geniposide Attenuates Hyperglycemia‐Induced Oxidative Stress and Inflammation by Activating the Nrf2 Signaling Pathway in Experimental Diabetic Retinopathy

Yuanyuan Tu, Lele Li, Linling Zhu, +6

Oxidative Medicine and Cellular Longevity

Apatinib enhanced anti-PD-1 therapy for colon cancer in mice via promoting PD-L1 expression

Xiaomin Cai, Bin Wei, Lele Li, +8

International Immunopharmacology

Anti-pd-1 TherapyImmunologyImmunotherapeuticsImmunotherapyApatinib Treatment +15

YAP via interacting with STAT3 regulates VEGF-induced angiogenesis in human retinal microvascular endothelial cells

Manhui Zhu, Xiaojuan Liu, Ying Wang, +9

Experimental Cell Research

Vegf-induced AngiogenesisAngiogenesisSignal TransductionOphthalmologySignaling Pathway +5

CSF1/CSF1R-mediated Crosstalk Between Choroidal Vascular Endothelial Cells and Macrophages Promotes Choroidal Neovascularization

Yamei Zhou, Jia Zeng, Yuanyuan Tu, +7

Investigative Ophthalmology & Visual Science

Inhibition of NAMPT decreases cell growth and enhances susceptibility to oxidative stress

Renhua Xu, Zhenwei Yuan, Lijuan Yang, +3

Oncology Reports

TNF-α released from retinal Müller cells aggravates retinal pigment epithelium cell apoptosis by upregulating mitophagy during diabetic retinopathy

Yu Liu, Lele Li, Ningxin Pan, +7

Biochemical and Biophysical Research Communications

Diabetic RetinopathyOcular DiseaseSignal TransductionRetinaOphthalmology +9

Inhibition of YAP ameliorates choroidal neovascularization via inhibiting endothelial cell proliferation.

Zhenzhen Yan, Haihong Shi, Rongrong Zhu, +5

PubMed

Long noncoding RNA glutathione peroxidase 3-antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age-related cataract.

Yuanyuan Tu, Lele Li, Bai Qin, +4

PubMed

Fruquintinib inhibits VEGF/VEGFR2 axis of choroidal endothelial cells and M1-type macrophages to protect against mouse laser-induced choroidal neovascularization

Xiaojuan Liu, Aisong Guo, Yuanyuan Tu, +7

Cell Death and Disease

Ocular DiseaseImmunologyChoroidal Endothelial CellsVegf/vegfr2 AxisM1 Polarization +15