Melatonin attenuates oxidative stress and inflammation of Müller cells in diabetic retinopathy via activating the Sirt1 pathway

Yuanyuan Tu, E Song, Zhenzhen Wang, +8

Biomedicine & Pharmacotherapy

Lipid PeroxidationCell DeathOxidative StressInflammationDiabetic Retinopathy +14

Targeted Noninvasive Treatment of Choroidal Neovascularization by Hybrid Cell-Membrane-Cloaked Biomimetic Nanoparticles

Manjing Li, Zhaojian Xu, Lu Zhang, +8

ACS Nano

NanoparticlesNanomedicineEngineeringOphthalmologyNanomaterials +8

Melatonin inhibits Müller cell activation and pro‐inflammatory cytokine production via upregulating the MEG3/miR‐204/Sirt1 axis in experimental diabetic retinopathy

Yuanyuan Tu, Manhui Zhu, Zhenzhen Wang, +9

Journal of Cellular Physiology

Prodrug of epigallocatechin-3-gallate alleviates choroidal neovascularization via down-regulating HIF-1α/VEGF/VEGFR2 pathway and M1 type macrophage/microglia polarization

Jiaowen Xu, Yuanyuan Tu, Ying Wang, +10

Biomedicine & Pharmacotherapy

Geniposide Attenuates Hyperglycemia‐Induced Oxidative Stress and Inflammation by Activating the Nrf2 Signaling Pathway in Experimental Diabetic Retinopathy

Yuanyuan Tu, Lele Li, Linling Zhu, +6

Oxidative Medicine and Cellular Longevity

Epigallocatechin-3-gallate stimulates autophagy and reduces apoptosis levels in retinal Müller cells under high-glucose conditions

Li Wang, Xiaodong Sun, Manhui Zhu, +5

Experimental Cell Research

Cell AutophagyMitophagyEpigallocatechin-3-gallate Stimulates AutophagyOphthalmologyApoptosis +10

A prodrug of epigallocatechin-3-gallate alleviates high glucose-induced pro-angiogenic factor production by inhibiting the ROS/TXNIP/NLRP3 inflammasome axis in retinal Müller cells

Jingxia Du, Ying Wang, Yuanyuan Tu, +8

Experimental Eye Research

InflammationOcular DiseaseOphthalmologyMedicineLipid Peroxidation +8

YAP via interacting with STAT3 regulates VEGF-induced angiogenesis in human retinal microvascular endothelial cells

Manhui Zhu, Xiaojuan Liu, Ying Wang, +9

Experimental Cell Research

Vegf-induced AngiogenesisAngiogenesisSignal TransductionOphthalmologySignaling Pathway +5

Dysfunctional Nurr1 promotes high glucose-induced Müller cell activation by up-regulating the NF-κB/NLRP3 inflammasome axis

Wendie Li, Xiaojuan Liu, Yuanyuan Tu, +7

Neuropeptides

Signal TransductionSignaling PathwayNf-κb/nlrp3 Inflammasome AxisMolecular PathwayMetabolic Signaling +6

Tissue factor induces VEGF expression via activation of the Wnt/β-catenin signaling pathway in ARPE-19 cells.

Ying Wang, Aimin Sang, Manhui Zhu, +4

PubMed