Giuseppina De Simone

Author

Institute of Biostructure and Bioimaging ORCID

Also Known As

De Simone G,, De Simone, G., De Simone, Giuseppina, G DE SIMONE, G De Simone, G Simone, G de Simone, G. De Simone, G. SIMONE, G. Simone

290

Publications

11.1K

Citations

H-Index

135

Concepts

All Affiliations

Institute of Biostructure and Bioimaging University of Florence University of Naples Federico II Institut des Biomolécules Max Mousseron École Nationale Supérieure de Chimie de Montpellier

About

Giuseppina De Simone is an author at Institute of Biostructure and Bioimaging specializing in biochemistry, natural sciences, and medicine.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Biochemistry	35	65	3.7K
2	Natural Sciences	33	60	3.7K
3	Medicine	30	53	3K
4	Engineering	12	13	742
5	Health Sciences	6	6	164

Giuseppina De Simone

116

Publications

6.7K

Citations

H-Index

Page 1

	Year	Citations
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX Vincenzo Alterio, Mika Hilvo, Anna Di Fiore, Proceedings of the National Academy of Sciences	2009	513
Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation Gianluca Canettieri, Lucia Di Marcotullio, Azzura Greco, Nature Cell Biology Molecular RegulationEpigeneticsTranscriptional RegulationSignaling PathwayCell Regulation	2010	321
Biochemical Characterization of CA IX, One of the Most Active Carbonic Anhydrase Isozymes Mika Hilvo, Lina Baranauskienė, Anna Maria Salzano, Journal of Biological Chemistry Proteinlipid InteractionProtein SecretionMolecular BiologyCytoskeletonPolysaccharide	2008	303
Carbonic Anhydrase Inhibitors: X-ray and Molecular Modeling Study for the Interaction of a Fluorescent Antitumor Sulfonamide with Isozyme II and IX Vincenzo Alterio, Rosa Maria Vitale, Simona Maria Monti, Journal of the American Chemical Society	2006	201
Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies Giuseppina De Simone, Anna Di Fiore, Valeria Menchise, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyMedicinal ChemistryBiochemistryNatural SciencesMedicine	2005	185
The crystal structure of a hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus 1 1Edited by R. Huber Giuseppina De Simone, Valeria Menchise, Giuseppe Manco, Journal of Molecular Biology Crystal StructureEngineeringBiochemistryNatural SciencesBiocatalysis	2001	159
Carbonic Anhydrase Inhibitors: Stacking with Phe131 Determines Active Site Binding Region of Inhibitors As Exemplified by the X-ray Crystal Structure of a Membrane-Impermeant Antitumor Sulfonamide Complexed with Isozyme II Valeria Menchise, Giuseppina De Simone, Vincenzo Alterio, Journal of Medicinal Chemistry Protein AssemblyCarbonic Anhydrase IiMolecular BiologyChemical BiologyIsozyme Ii	2005	156
Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a <scp>d</scp> -lysine-based chiral PNA–DNA duplex Valeria Menchise, Giuseppina De Simone, Tullia Tedeschi, Proceedings of the National Academy of Sciences	2003	153
A snapshot of a transition state analogue of a novel thermophilic esterase belonging to the subfamily of mammalian hormone-sensitive lipase 1 1Edited by D. Rees Giuseppina De Simone, Stefania Galdiero, Giuseppe Manco, Journal of Molecular Biology BiosynthesisBioorganic ChemistryBiochemistryNatural SciencesD. Rees	2000	141
Out of the active site binding pocket for carbonic anhydrase inhibitors Katia D’Ambrosio, Simone Carradori, Simona Maria Monti, Chemical Communications EngineeringAldo-keto ReductaseOrganic ChemistryChemical BiologyEnzymatic Modification	2014	130

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