Giuseppina De Simone

Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX

Vincenzo Alterio, Mika Hilvo, Anna Di Fiore et al. · Proceedings of the National Academy of Sciences · 2009 · 513 citations · Full text

Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation

Gianluca Canettieri, Lucia Di Marcotullio, Azzura Greco et al. · Nature Cell Biology · 2010 · 321 citations

Molecular Regulation, Epigenetics, Transcriptional Regulation +16

Biochemical Characterization of CA IX, One of the Most Active Carbonic Anhydrase Isozymes

Mika Hilvo, Lina Baranauskienė, Anna Maria Salzano et al. · Journal of Biological Chemistry · 2008 · 303 citations · Full text

Proteinlipid Interaction, Protein Secretion, Molecular Biology +22

Carbonic Anhydrase Inhibitors:  X-ray and Molecular Modeling Study for the Interaction of a Fluorescent Antitumor Sulfonamide with Isozyme II and IX

Vincenzo Alterio, Rosa Maria Vitale, Simona Maria Monti et al. · Journal of the American Chemical Society · 2006 · 201 citations

Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies

Giuseppina De Simone, Anna Di Fiore, Valeria Menchise et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 185 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +11