Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis

Feiyang Ma, Olesya Plazyo, Allison C. Billi, +25

Nature Communications

Contribution of plasma cells and B cells to hidradenitis suppurativa pathogenesis

Jóhann E. Guðjónsson, Lam C. Tsoi, Feiyang Ma, +30

JCI Insight

Tyrosine KinaseImmune RegulationImmunologySuppurativa PathogenesisImmunologic Mechanism +25

Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms

Frank M. Davis, Lam C. Tsoi, William J. Melvin, +14

The Journal of Experimental Medicine

Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation

Allison C. Billi, Feiyang Ma, Olesya Plazyo, +14

Science Translational Medicine

Epigenetic regulation of the PGE2 pathway modulates macrophage phenotype in normal and pathologic wound repair

Frank M. Davis, Lam C. Tsoi, Rachael Wasikowski, +18

JCI Insight

ImmunologyImmune RegulationCell DeathRenal InflammationInnate Immunity +23

Single-cell transcriptomics reveals distinct effector profiles of infiltrating T cells in lupus skin and kidney

Garrett S. Dunlap, Allison C. Billi, Xianying Xing, +8

JCI Insight

Lupus SkinT-regulatory CellImmunologyImmune RegulationNk Cells +17

Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis

Feiyang Ma, Pei‐Suen Tsou, Mehrnaz Gharaee‐Kermani, +22

Nature Communications

Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris

Shuai Shao, Jiaoling Chen, William R. Swindell, +17

JCI Insight

ImmunologyDermatologyPhospholipase A2InflammationBiosynthesis +18

Differential cell composition and split epidermal differentiation in human palm, sole, and hip skin

Julie Wiedemann, Allison C. Billi, Federico Bocci, +15

Cell Reports

GeneticsCell DifferentiationDermatologyCell SpecializationDifferential Cell Composition +18

IL18-containing 5-gene signature distinguishes histologically identical dermatomyositis and lupus erythematosus skin lesions

Lam C. Tsoi, Mehrnaz Gharaee‐Kermani, Céline C. Berthier, +10

JCI Insight

ImmunodeficienciesImmunologyImmune RegulationInnate ImmunityDermatology +23