Geoffrey Del Rosario

Author

WuXi AppTec (China)

Also Known As

Geoffrey Del Rosario, Geoffrey del Rosario

Publications

Citations

H-Index

Concepts

All Affiliations

WuXi AppTec (China)Genesys (United States)Amgen (United States)

About

Geoffrey Del Rosario is an author at WuXi AppTec (China) specializing in drug discovery, pharmacology, and medicine.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	3	3	148
2	Natural Sciences	2	2	72
3	Biochemistry	2	2	129
4	Biomolecular Engineering	2	2	129
5	Engineering	1	1	76

Geoffrey Del Rosario

Publications

Citations

H-Index

Page 1

	Year	Citations
Antibody Conjugation of a Chimeric BET Degrader Enables <i>in vivo</i> Activity Thomas H. Pillow, Pragya Adhikari, Robert A. Blake, ChemMedChem	2019	178
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy Peter S. Dragovich, Thomas H. Pillow, Robert A. Blake, Journal of Medicinal Chemistry	2021	159
Decoupling stability and release in disulfide bonds with antibody-small molecule conjugates Thomas H. Pillow, Jack Sadowsky, Donglu Zhang, Chemical Science	2016	126
Bridging the Gap between Preclinical and Clinical Studies Using Pharmacokinetic–Pharmacodynamic Modeling: An Analysis of GDC-0973, a MEK Inhibitor Harvey Wong, Laurent Vernillet, Amy Peterson, Clinical Cancer Research	2012	79
Modulating Antibody–Drug Conjugate Payload Metabolism by Conjugation Site and Linker Modification Dian Su, Katherine R. Kozak, Jack Sadowsky, Bioconjugate Chemistry Medicinal ChemistryDrug TargetingEngineeringBiochemistryPolymer-drug Conjugate	2018	76
Modulating Therapeutic Activity and Toxicity of Pyrrolobenzodiazepine Antibody–Drug Conjugates with Self-Immolative Disulfide Linkers Thomas H. Pillow, Melissa M. Schutten, Shang‐Fan Yu, Molecular Cancer Therapeutics	2017	69
An Anti–CLL-1 Antibody–Drug Conjugate for the Treatment of Acute Myeloid Leukemia Bing Zheng, Shang‐Fan Yu, Geoffrey Del Rosario, Clinical Cancer Research	2018	64
Development of Efficient Chemistry to Generate Site-Specific Disulfide-Linked Protein– and Peptide–Payload Conjugates: Application to THIOMAB Antibody–Drug Conjugates Jack Sadowsky, Thomas H. Pillow, Jinhua Chen, Bioconjugate Chemistry	2017	59
High-Resolution Accurate-Mass Mass Spectrometry Enabling In-Depth Characterization of <i>in Vivo</i> Biotransformations for Intact Antibody-Drug Conjugates Jintang He, Dian Su, Carl Ng, Analytical Chemistry Biological Mass SpectrometryMedicinal ChemistryBioanalysisImmunochemistryAnalytical Chemistry	2017	53
A homogeneous high-DAR antibody–drug conjugate platform combining THIOMAB antibodies and XTEN polypeptides Neelie T. Zacharias, Vladimir N. Podust, Kimberly K. Kajihara, Chemical Science	2022	51

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