Geoffrey Del Rosario

Antibody Conjugation of a Chimeric BET Degrader Enables <i>in vivo</i> Activity

Thomas H. Pillow, Pragya Adhikari, Robert A. Blake et al. · ChemMedChem · 2019 · 178 citations

Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy

Peter S. Dragovich, Thomas H. Pillow, Robert A. Blake et al. · Journal of Medicinal Chemistry · 2021 · 159 citations

Decoupling stability and release in disulfide bonds with antibody-small molecule conjugates

Thomas H. Pillow, Jack Sadowsky, Donglu Zhang et al. · Chemical Science · 2016 · 126 citations · Full text

Bridging the Gap between Preclinical and Clinical Studies Using Pharmacokinetic–Pharmacodynamic Modeling: An Analysis of GDC-0973, a MEK Inhibitor

Harvey Wong, Laurent Vernillet, Amy Peterson et al. · Clinical Cancer Research · 2012 · 79 citations

Modulating Antibody–Drug Conjugate Payload Metabolism by Conjugation Site and Linker Modification

Dian Su, Katherine R. Kozak, Jack Sadowsky et al. · Bioconjugate Chemistry · 2018 · 76 citations

Medicinal Chemistry, Drug Targeting, Engineering +15