Cisplatin Preferentially Binds Mitochondrial DNA and Voltage-Dependent Anion Channel Protein in the Mitochondrial Membrane of Head and Neck Squamous Cell Carcinoma: Possible Role in Apoptosis

Zejia Yang, Lisa M. Schumaker, Merrill J. Egorin, +3

Clinical Cancer Research

Somatic mutation and gain of copy number of PIK3CA in human breast cancer

Guojun Wu, Mingzhao Xing, Elizabeth Mambo, +9

Breast Cancer Research

DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development.

Guojun Wu, Shuji Nomoto, Mohammad Obaidul Hoque, +14

PubMed

Molecular BiologyGene CharacterizationP63 GeneTumor BiologyTranscriptional Regulation +18

Uncommon Mutation, but Common Amplifications, of the<i>PIK3CA</i>Gene in Thyroid Tumors

Guojun Wu, Elizabeth Mambo, Zhongmin Guo, +7

The Journal of Clinical Endocrinology & Metabolism

Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations

Elizabeth Mambo, Xiangqun Gao, Yoram Cohen, +3

Proceedings of the National Academy of Sciences

Methylation of the thyroid-stimulating hormone receptor gene in epithelial thyroid tumors: a marker of malignancy and a cause of gene silencing.

Mingzhao Xing, Henning Usadel, Yoram Cohen, +9

PubMed

Epigenetic ChangeGeneticsDna MethylationPathologyEpigenetics +17

Quantitative Gstp1 Methylation Clearly Distinguishes Benign Prostatic Tissue And Limited Prostate Adenocarcinoma

Susan Harden, Zhongmin Guo, Jonathan I. Epstein, +1

The Journal of Urology

Dna MethylationPathologyGstp1 MethylationEpigeneticsTumor Biology +16

Differential expression of microRNA in peripheral blood mononuclear cells as specific biomarker for major depressive disorder patients

Huimin Fan, Xinyang Sun, Wei Guo, +7

Journal of Psychiatric Research

Specific BiomarkerPsychiatryDifferential ExpressionMedicineSubcortical Ischemic Depression +9

DeltaNp63alpha up-regulates the Hsp70 gene in human cancer.

Guojun Wu, Motonobu Osada, Zhongmin Guo, +14

PubMed

Transcriptional RegulationSignaling PathwayCell RegulationNatural SciencesTranscription Regulation +12

GPx3 promoter hypermethylation is a frequent event in human cancer and is associated with tumorigenesis and chemotherapy response

Baishen Chen, Xi Rao, Michael G. House, +3

Cancer Letters

Frequent EventCancer ResearchOncologyChemotherapy ResponseMedicine +8