MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock

Qun Zhao, Xianxi Wang, Leif D. Nelin, +8

The Journal of Experimental Medicine

Increased Inflammation, Impaired Bacterial Clearance, and Metabolic Disruption after Gram-Negative Sepsis in <i>Mkp-1</i> -Deficient Mice

W. Joshua Frazier, Xianxi Wang, Lyn M. Wancket, +4

The Journal of Immunology

XPO1 Inhibition using Selinexor Synergizes with Chemotherapy in Acute Myeloid Leukemia by Targeting DNA Repair and Restoring Topoisomerase IIα to the Nucleus

Parvathi Ranganathan, Trinayan Kashyap, Xueyan Yu, +11

Clinical Cancer Research

Knockout of <i>Mkp-1</i> Enhances the Host Inflammatory Responses to Gram-Positive Bacteria

Xianxi Wang, Xiaomei Meng, Joshua R. Kuhlman, +3

The Journal of Immunology

Glutathione Reductase Facilitates Host Defense by Sustaining Phagocytic Oxidative Burst and Promoting the Development of Neutrophil Extracellular Traps

Jing Yan, Xiaomei Meng, Lyn M. Wancket, +6

The Journal of Immunology

Microbial PathogensLipid PeroxidationImmunologyCell DeathPhagocytic Oxidative Burst +16

Resveratrol prevents hypoxia-induced arginase II expression and proliferation of human pulmonary artery smooth muscle cells via Akt-dependent signaling

Bernadette Chen, Jianjing Xue, Xiaomei Meng, +3

American Journal of Physiology-Lung Cellular and Molecular Physiology

InflammationPulmonary Arterial HypertensionBiochemistryMedicineArginase Ii +12

Inducible Nitric-oxide Synthase Expression Is Regulated by Mitogen-activated Protein Kinase Phosphatase-1

Xianxi Wang, Qun Zhao, Ranyia Matta, +4

Journal of Biological Chemistry

The role of MAP kinase phosphatase-1 in the protective mechanism of dexamethasone against endotoxemia

Xianxi Wang, Leif D. Nelin, Joshua R. Kuhlman, +2

Life Sciences

InflammationSignal TransductionBiochemistryCell SignalingNatural Sciences +13

Glutathione reductase is essential for host defense against bacterial infection

Jing Yan, Melissa Ralston, Xiaomei Meng, +7

Free Radical Biology and Medicine

BiochemistryVirulence FactorMicrobiologyInfection ControlMolecular Microbiology +6

Mitogen-activated Protein Kinase Phosphatase (Mkp)-1 Protects Mice against Acetaminophen-induced Hepatic Injury

Lyn M. Wancket, Xiaomei Meng, Lynette K. Rogers

Toxicologic Pathology