A Route to the Thapsigargins from (<i>S</i>)‐Carvone Providing a Substrate‐Controlled Total Synthesis of Trilobolide, Nortrilobolide, and Thapsivillosin F

Steven F. Oliver, Klemens Högenauer, Oliver Simić, +3

Angewandte Chemie International Edition

Structural AnaloguesBioorganic ChemistrySubstrate-controlled Total SynthesisBiochemistryNatural Sciences +11

Synthesis of Borondipyrromethene (BODIPY)-Labeled Sphingosine Derivatives by Cross-metathesis Reaction

Carsten Peters, Andreas Billich, Michael Ghobrial, +3

The Journal of Organic Chemistry

Combinatorial ChemistryMedicinal ChemistryBioorganic ChemistryBiochemistryNatural Sciences +11

G-Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5) Agonists Reduce the Production of Proinflammatory Cytokines and Stabilize the Alternative Macrophage Phenotype

Klemens Högenauer, Luca Arista, Niko Schmiedeberg, +8

Journal of Medicinal Chemistry

ImmunologyImmune RegulationImmunologic MechanismCholangiopathiesMurine Gpbar1 +24

Total Synthesis of Five Thapsigargins: Guaianolide Natural Products Exhibiting Sub‐Nanomolar SERCA Inhibition

Stephen P. Andrews, Matthew Ball, Frank Wierschem, +8

Chemistry - A European Journal

Five ThapsigarginsGuaianolide Natural ProductsMedicinal ChemistryCombinatorial ChemistryBiochemistry +9

Synthesis of the thapsigargins

Steven V. Ley, Alessandra Antonello, Emily P. Balskus, +12

Proceedings of the National Academy of Sciences

One-step labelling of sphingolipids via a scrambling cross-metathesis reaction

Peter Nußbaumer, Peter Ettmayer, Carsten Peters, +2

Chemical Communications

Asymmetric CatalysisProteinlipid InteractionCross-coupling ReactionEnantioselective SynthesisBioorganic Chemistry +11

Synthesis and acetylcholinesterase inhibition of 5-desamino huperzine A derivatives

Klemens Högenauer, Karl Baumann, Albert Enz, +1

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyMedicinal ChemistryPharmaceutical ChemistryBioorganic ChemistryDerivatives +8

A Novel Palladium-Catalyzed Intramolecular Redox Reaction

Klemens Högenauer, Johann Mulzer

Organic Letters

Cross-coupling ReactionEngineeringNew TypePalladium AcetateOrganic Chemistry +8

Phosphorylation by Sphingosine Kinase 2 is Essential for in vivo Potency of FTY720 Analogues

Klemens Högenauer, Andreas Billich, Charles Pally, +4

ChemMedChem

Molecular RegulationImmunologySphingosine Kinase 2Molecular PharmacologySignaling Pathway +14

A Route to the Thapsigargins from (<i>S</i>)‐Carvone Providing a Substrate‐Controlled Total Synthesis of Trilobolide, Nortrilobolide, and Thapsivillosin F

Steven F. Oliver, Klemens Högenauer, Oliver Simić, +3

Angewandte Chemie

Darunter TrilobolidBioorganic ChemistryBiochemistryNatural SciencesSubstrate‐controlled Total Synthesis +12