Lysophosphatidylcholine plays an essential role in the mitogenic effect of oxidized low density lipoprotein on murine macrophages.

Masakazu Sakai, Akihiro Miyazaki, Hideki Hakamata, +5

Journal of Biological Chemistry

Lipid PeroxidationCellular PhysiologyOxidative StressInflammationMetabolic Syndrome +16

Intravenous Injection of Rabbit Apolipoprotein A-I Inhibits the Progression of Atherosclerosis in Cholesterol-Fed Rabbits

Akira Miyazaki, Shin Sakuma, Wataru Morikawa, +11

Arteriosclerosis Thrombosis and Vascular Biology

Cost-effectiveness of intensive insulin therapy for type 2 diabetes: a 10-year follow-up of the Kumamoto study

Nakayasu Wake, Akinori Hisashige, Takafumi Katayama, +5

Diabetes Research and Clinical Practice

ObesityMetabolic SyndromeDiabetes ManagementHealth EconomicsIntensive Insulin Therapy +9

Two Intracellular Signaling Pathways for Activation of Protein Kinase C Are Involved in Oxidized Low-Density Lipoprotein–Induced Macrophage Growth

Takeshi Matsumura, Masakazu Sakai, Shozo Kobori, +6

Arteriosclerosis Thrombosis and Vascular Biology

The Scavenger Receptor Serves as a Route for Internalization of Lysophosphatidylcholine in Oxidized Low Density Lipoprotein-induced Macrophage Proliferation

Masakazu Sakai, Akira Miyazaki, Hideki Hakamata, +5

Journal of Biological Chemistry

Expression of Class A Scavenger Receptor Is Enhanced by High Glucose in Vitro and under Diabetic Conditions in Vivo

Kaori Takaki, Masakazu Sakai, Yu-ichiro Sakamoto, +2

Journal of Biological Chemistry

Statins Suppress Oxidized Low Density Lipoprotein-induced Macrophage Proliferation by Inactivation of the Small G Protein-p38 MAPK Pathway

Takafumi Senokuchi, Takeshi Matsumura, Masakazu Sakai, +10

Journal of Biological Chemistry

InflammationLow Density LipoproteinFarnesyl Transferase InhibitorOxysterolAtherosclerosis +13

HMG-CoA reductase inhibitors suppress macrophage growth induced by oxidized low density lipoprotein

Masakazu Sakai, Shozo Kobori, Takeshi Matsumura, +6

Atherosclerosis

InflammationOxysterolBiochemistryLipid PeroxidationImmunology +9

Lysophosphatidylcholine Potentiates the Mitogenic Activity of Modified LDL for Human Monocyte–Derived Macrophages

Masakazu Sakai, Akira Miyazaki, Hideki Hakamata, +5

Arteriosclerosis Thrombosis and Vascular Biology

Induction of Murine Macrophage Growth by Oxidized Low Density Lipoprotein Is Mediated by Granulocyte Macrophage Colony-stimulating Factor

Takeshi Biwa, Hideki Hakamata, Masakazu Sakai, +5

Journal of Biological Chemistry