Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

Jun Lan, Jiwan Ge, Jinfang Yu, +8

Nature

Human neutralizing antibodies elicited by SARS-CoV-2 infection

Bin Ju, Qi Zhang, Jiwan Ge, +21

Nature

VaccinationSars-cov-2 InfectionVaccine TargetHumoral ResponseImmunology +3

Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4

Nianshuang Wang, Xuanling Shi, Liwei Jiang, +11

Cell Research

Human Receptor Dpp4Viral PathogenesisMolecular BiologyAnalytical UltracentrifugationViral Structural Protein +16

Small Molecules Blocking the Entry of Severe Acute Respiratory Syndrome Coronavirus into Host Cells

Ling Yi, Zhengquan Li, Kehu Yuan, +21

Journal of Virology

Surface Spike ProteinViral ReplicationViral PathogenesisImmunologyAntiviral Drug +19

Potent human neutralizing antibodies elicited by SARS-CoV-2 infection

Bin Ju, Qi Zhang, Xiangyang Ge, +19

ImmunologyViral PathogenesisRbd BindingRbd-specific Monoclonal AntibodiesViral Structural Protein +15

Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species

Ruoke Wang, Qi Zhang, Jiwan Ge, +17

Immunity

Viral EvolutionSignal TransductionMedicineImmunologyViral Pathogenesis +8

Potent Neutralization of MERS-CoV by Human Neutralizing Monoclonal Antibodies to the Viral Spike Glycoprotein

Liwei Jiang, Nianshuang Wang, Teng Zuo, +12

Science Translational Medicine

Crystal structure of the 2019-nCoV spike receptor-binding domain bound with the ACE2 receptor

Jun Lan, Jiwan Ge, Jinfang Yu, +8

Crystal StructureViral DiagnosticsImmunologyViral PathogenesisMolecular Biology +16

Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry

Jiwan Ge, Ruoke Wang, Bin Ju, +18

Nature Communications

Deep learning guided optimization of human antibody against SARS-CoV-2 variants with broad neutralization

Sisi Shan, Shitong Luo, Ziqing Yang, +12

Proceedings of the National Academy of Sciences

Significance Sars-cov-2ImmunologyImmunodominanceViral Structural ProteinBroad-spectrum Vaccines +15