Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

Jun Lan, Jiwan Ge, Jinfang Yu, +8

Nature

Human neutralizing antibodies elicited by SARS-CoV-2 infection

Bin Ju, Qi Zhang, Jiwan Ge, +21

Nature

VaccinationSars-cov-2 InfectionVaccine TargetHumoral ResponseImmunology +3

The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity

Qianqian Li, Jiajing Wu, Jianhui Nie, +17

Cell

Viral EvolutionViral PersistenceSars-cov-2 SpikeViral PathogenesisImmunology +5

Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro

Qi Zhang, Catherine Zhengzheng Chen, Manju Swaroop, +14

Cell Discovery

Crystal structure of the 2019-nCoV spike receptor-binding domain bound with the ACE2 receptor

Jun Lan, Jiwan Ge, Jinfang Yu, +8

Crystal StructureViral DiagnosticsImmunologyViral PathogenesisMolecular Biology +16

Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry

Jiwan Ge, Ruoke Wang, Bin Ju, +18

Nature Communications

Deep learning guided optimization of human antibody against SARS-CoV-2 variants with broad neutralization

Sisi Shan, Shitong Luo, Ziqing Yang, +12

Proceedings of the National Academy of Sciences

Significance Sars-cov-2ImmunologyImmunodominanceViral Structural ProteinBroad-spectrum Vaccines +15

Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2

Qi Zhang, Bin Ju, Jiwan Ge, +26

Nature Communications

Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies

Dongyan Zhou, Jasper Fuk‐Woo Chan, Biao Zhou, +25

Cell Host & Microbe

Systemic Neutralizing AntibodiesImmunologyRespiratory InfectionNasal TurbinatesRobust Sars-cov-2 Infection +3

Somatic SF3B1 hotspot mutation in prolactinomas

Chuzhong Li, Weiyan Xie, Jared S. Rosenblum, +22

Nature Communications