Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit

Thomas Bertero, Katherine A. Cottrill, Yu Lu, +22

Cell Reports

MechanobiologyPulmonary Arterial HypertensionSignal TransductionMolecular PhysiologyPulmonary Circulation +10

Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension

Thomas Bertero, Yu Lu, Sofia Annis, +18

Journal of Clinical Investigation

Transcriptional RegulationSubordinate Mirna PathwaysCell SignalingMolecular SignalingPh Progression +16

Bone Morphogenetic Protein‐2 Decreases MicroRNA‐30b and MicroRNA‐30c to Promote Vascular Smooth Muscle Cell Calcification

Joshua Balderman, Hae‐Young Lee, Christopher E. Mahoney, +7

Journal of the American Heart Association

Genetic and hypoxic alterations of the micro <scp>RNA</scp> ‐210‐ <scp>ISCU</scp> 1/2 axis promote iron–sulfur deficiency and pulmonary hypertension

Kevin P. White, Yu Lu, Sofia Annis, +31

EMBO Molecular Medicine

A nanoscale, multi-parametric flow cytometry-based platform to study mitochondrial heterogeneity and mitochondrial DNA dynamics

J. Macdonald, Alisha M. Bothun, Sofia Annis, +7

Communications Biology

The MicroRNA-130/301 Family Controls Vasoconstriction in Pulmonary Hypertension

Thomas Bertero, Katherine A. Cottrill, Adrienn Krauszman, +8

Journal of Biological Chemistry

HypertensionPulmonary Arterial HypertensionPhysiologyPulmonary PhysiologyPulmonary Hypertension +5

A YAP/TAZ-miR-130/301 molecular circuit exerts systems-level control of fibrosis in a network of human diseases and physiologic conditions

Thomas Bertero, Katherine A. Cottrill, Sofia Annis, +9

Scientific Reports

An Argonaute 2 switch regulates circulating miR-210 to coordinate hypoxic adaptation across cells

Andrew Hale, Changjin Lee, Sofia Annis, +9

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Complex OrganismsRedox BiologyCellular PhysiologyArgonaute 2Oxidative Stress +17

A mitochondria-specific mutational signature of aging: increased rate of A &amp;gt; G substitutions on the heavy strand

Alina G. Mikhailova, Alina A. Mikhailova, Kristina Ushakova, +27

Nucleic Acids Research

Integration of mtDNA pseudogenes into the nuclear genome coincides with speciation of the human genus. A hypothesis

Konstantin Gunbin, Leonid Peshkin, Konstantin Popadin, +3

Mitochondrion

DnaPhylogeneticsComparative GenomicsGeneticsEvolutionary Biology +10