Concepedia

Michael P. A. Lyle

MP

8

Publications

580

Citations

8

H-Index

2004

Active since

Affiliations

Simon Fraser University(Current)

Welichem Biotech (Canada)

Michael P. A. Lyle is an author at Simon Fraser University specializing in organic chemistry, chemistry, and catalysis.

Top concepts

Publications per year

2004–2020

8

Publications

8

A Phase 1 Study of SLC-0111, a Novel Inhibitor of Carbonic Anhydrase IX, in Patients With Advanced Solid Tumors

Paul C. McDonald, Stephen Chia, Philippe L. Bédard et al. · American Journal of Clinical Oncology · 2020 · 235 citations · Full text

Enantioselective Friedel−Crafts Alkylation Reactions Catalyzed by a Chiral Nonracemic <i>C</i><sub>2</sub>-Symmetric 2,2‘-Bipyridyl Copper(II) Complex

Michael P. A. Lyle, N.D. Draper, Peter D. Wilson · Organic Letters · 2005 · 109 citations

Substituted 6-amino-4H-[1,2]dithiolo[4,3-b]pyrrol-5-ones: Synthesis, structure–activity relationships, and cytotoxic activity on selected human cancer cell lines

Bin Li, Michael P. A. Lyle, Genhui Chen et al. · Bioorganic & Medicinal Chemistry · 2007 · 64 citations

, , +8

Synthesis of a New Chiral Nonracemic <i>C</i><sub>2</sub>-Symmetric 2,2‘-Bipyridyl Ligand and Its Application in Copper(I)-Catalyzed Enantioselective Cyclopropanation Reactions

Michael P. A. Lyle, Peter D. Wilson · Organic Letters · 2004 · 60 citations

, , +13

Stroma secreted IL6 selects for “stem-like” population and alters pancreatic tumor microenvironment by reprogramming metabolic pathways

Kousik Kesh, Vanessa T. Garrido, Austin R. Dosch et al. · Cell Death and Disease · 2020 · 40 citations · Full text

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