Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes

Jacob A. Tennessen, Abigail W. Bigham, Timothy D. O’Connor, +20

Science

GeneticsGenetic EpidemiologyMolecular GeneticsGenomicsGenetic Medicine +29

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

Brian J. O’Roak, Laura Vives, Wenqing Fu, +23

Science

Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants

Wenqing Fu, Timothy D. O’Connor, Goo Jun, +11

Nature

Evolutionary History and Adaptation from High-Coverage Whole-Genome Sequences of Diverse African Hunter-Gatherers

Joseph Lachance, Benjamin Vernot, Clara C. Elbers, +10

Cell

PhylogeneticsEvolutionary HistoryGenome StudyNatural SciencesGenetics +10

Genomic Dissection of Population Substructure of Han Chinese and Its Implication in Association Studies

Shuhua Xu, Xianyong Yin, Shilin Li, +21

The American Journal of Human Genetics

Exonic Transcription Factor Binding Directs Codon Choice and Affects Protein Evolution

Andrew B. Stergachis, Eric Haugen, Anthony Shafer, +8

Science

GeneticsGenomic MechanismMolecular BiologyMolecular GeneticsGenomics +16

Identifying and Interpreting Apparent Neanderthal Ancestry in African Individuals

Lu Chen, Aaron B. Wolf, Wenqing Fu, +2

Cell

EthnicityAfrican IndividualsHuman VariationPaleoanthropologyHuman Origin +4

A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome

Rasika A. Mathias, Margaret A. Taub, Christopher R. Gignoux, +58

Nature Communications

Y Chromosomes of 40% Chinese Descend from Three Neolithic Super-Grandfathers

Shi Yan, Chuan‐Chao Wang, Hongxiang Zheng, +13

PLoS ONE

Adaptive Evolution of the FADS Gene Cluster within Africa

Rasika A. Mathias, Wenqing Fu, Joshua M. Akey, +6

PLoS ONE