Ian A. Pringle

Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial

Eric W.F.W. Alton, David K Armstrong, Deborah Ashby et al. · The Lancet Respiratory Medicine · 2015 · 417 citations · Full text

Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis

Eric W.F.W. Alton, Jeffrey M. Beekman, A. Christopher Boyd et al. · Thorax · 2016 · 141 citations · Full text

Translational Medicine, Lung Gene Transfer, Viral Diagnostics +15

Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung

Gerry McLachlan, H Davidson, Emma Holder et al. · Gene Therapy · 2011 · 101 citations

Aerosol Delivery, Immunology, Respiratory Infection +6

The use of CpG-free plasmids to mediate persistent gene expression following repeated aerosol delivery of pDNA/PEI complexes

Lee A. Davies, Stephen C. Hyde, G. Nunez-Alonso et al. · Biomaterials · 2012 · 45 citations

Aerosol Delivery, Cpg-free Plasmids, Natural Sciences +8

A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis

Eric W.F.W. Alton, David K Armstrong, Deborah Ashby et al. · Efficacy and Mechanism Evaluation · 2016 · 45 citations · Full text

Secondary Clinical Outcomes, Inflammatory Lung Disease, In Vivo Gene Therapy +16